Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
WFDC13WAP four-disulfide core domain protein 13; Putative acid-stable proteinase inhibitor. (93 aa)    
Predicted Functional Partners:
WFDC11
Protein WFDC11; WAP four-disulfide core domain 11.
   
  
 0.727
SPINT4
Serine peptidase inhibitor, Kunitz type 4.
   
 
 0.721
WFDC9
Protein WFDC9; WAP four-disulfide core domain 9.
   
  
 0.703
WFDC10A
WAP four-disulfide core domain 10A.
   
  
 0.638
WFDC10B
Protein WFDC10B; WAP four-disulfide core domain 10B.
   
  
 0.629
WFDC3
WAP four-disulfide core domain 3.
   
 
 0.589
DNTTIP1
Deoxynucleotidyltransferase terminal-interacting protein 1; Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro). Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA.
   
  
 0.508
WFDC2
WAP four-disulfide core domain protein 2; Broad range protease inhibitor.
      
 0.485
WFDC6
WAP four-disulfide core domain 6.
   
 
 0.478
WFDC5
WAP four-disulfide core domain protein 5; Putative acid-stable proteinase inhibitor.
   
 
 0.474
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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