Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WFDC6WAP four-disulfide core domain 6. (86 aa)    
Predicted Functional Partners:
SPINT4
Serine peptidase inhibitor, Kunitz type 4.
      
 0.812
WFDC8
WAP four-disulfide core domain 8.
   
  
 0.778
EPPIN-WFDC6
EPPIN-WFDC6 readthrough.
   
  
0.522
WFDC13
WAP four-disulfide core domain protein 13; Putative acid-stable proteinase inhibitor.
   
 
 0.478
WFDC10A
WAP four-disulfide core domain 10A.
   
  
 0.469
SCGB1D1
Secretoglobin family 1D member 1; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones.
   
  
 0.456
WFDC10B
Protein WFDC10B; WAP four-disulfide core domain 10B.
   
  
 0.410
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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