Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WSCD1WSC domain containing 1. (575 aa)    
Predicted Functional Partners:
SEZ6
Seizure protein 6 homolog; May play a role in cell-cell recognition and in neuronal membrane signaling. Seems to be important for the achievement of the necessary balance between dendrite elongation and branching during the elaboration of a complex dendritic arbor. Involved in the development of appropriate excitatory synaptic connectivity (By similarity). Belongs to the SEZ6 family.
   
 
 0.479
RNF175
Ring finger protein 175.
      
 0.470
SDF2
Stromal cell derived factor 2.
    
 
 0.461
KCNAB3
Voltage-gated potassium channel subunit beta-3; Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters the functional properties of Kv1.5.
   
  
 0.456
TMC5
Transmembrane channel-like protein 5; Probable ion channel.
      
 0.437
MYCBPAP
MYCBP-associated protein; May play a role in spermatogenesis. May be involved in synaptic processes (By similarity).
     
 0.425
MANEA
Glycoprotein endo-alpha-1,2-mannosidase; Mannosidase endo-alpha.
   
  
 0.405
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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