Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
XGXg glycoprotein; Belongs to the CD99 family. (195 aa)    
Predicted Functional Partners:
CD99
CD99 antigen; Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Involved in T-cell adhesion processes (By similarity).
 
  
 0.892
ARSD
Arylsulfatase D.
   
  
 0.767
ARSF
Arylsulfatase F.
   
  
 0.766
ARSL
Arylsulfatase L; May be essential for the correct composition of cartilage and bone matrix during development. Has no activity toward steroid sulfates.
      
 0.730
STS
Steryl-sulfatase; Catalyzes the conversion of sulfated steroid precursors, such as dehydroepiandrosterone sulfate (DHEA-S) and estrone sulfate to the free steroid.
      
 0.710
SMIM9
Small integral membrane protein 9.
      
 0.495
OPN1MW3
Opsin 1, medium wave sensitive 3.
      
 0.465
CLDN34
Claudin-34; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
   
  
 0.455
CD99L2
CD99 antigen-like protein 2; Plays a role in a late step of leukocyte extravasation helping cells to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1 (By similarity). Homophilic adhesion molecule, but these interactions may not be required for cell aggregation (By similarity); Belongs to the CD99 family.
   
  
 0.403
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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