Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZBTB45Zinc finger and BTB domain-containing protein 45; May be involved in transcriptional regulation (Probable). In the central nervous system, may play a role in glial cell differentiation (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family. (511 aa)    
Predicted Functional Partners:
ZBTB20
Zinc finger and BTB domain-containing protein 20; May be a transcription factor that may be involved in hematopoiesis, oncogenesis, and immune responses. Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal (By similarity).
   
 
0.851
ZNF668
Zinc finger protein 668; May be involved in transcriptional regulation.
   
   
0.614
FAM185A
Protein FAM185A; Family with sequence similarity 185 member A.
   
  
 0.554
CCDC188
Coiled-coil domain containing 188.
      
 0.476
BTBD9
BTB/POZ domain-containing protein 9; BTB domain containing 9.
   
  
 0.470
ZNF131
Zinc finger protein 131; Plays a role during development and organogenesis as well as in the function of the adult central nervous system (By similarity). May be involved in transcriptional regulation as a repressor of ESR1/ER-alpha signaling.
    
  
0.457
SAMD10
Sterile alpha motif domain containing 10.
   
  
 0.434
SLC35G4
Solute carrier family 35 member G4.
      
 0.425
FAM76B
Protein FAM76B; Family with sequence similarity 76 member B; Belongs to the FAM76 family.
      
 0.416
UBALD1
UBA-like domain-containing protein 1; UBA like domain containing 1.
   
  
 0.413
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.