| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADNP2 | SLC66A2 | ENSP00000262198 | ENSP00000380880 | Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation. | Solute carrier family 66 member 2. | 0.518 |
| ADNP2 | SMIM21 | ENSP00000262198 | ENSP00000462106 | Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation. | Small integral membrane protein 21. | 0.424 |
| ADNP2 | ZNF407 | ENSP00000262198 | ENSP00000299687 | Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation. | Zinc finger protein 407; May be involved in transcriptional regulation. | 0.582 |
| ADNP2 | ZNF516 | ENSP00000262198 | ENSP00000394757 | Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation. | Zinc finger protein 516; Transcriptional regulator that binds to the promoter and activates the transcription of genes promoting brown adipose tissue (BAT) differentiation. Among brown adipose tissue-specific genes, binds the proximal region of the promoter of the UCP1 gene to activate its transcription and thereby regulate thermogenesis (By similarity). May also play a role in the cellular response to replication stress. | 0.437 |
| NAA50 | ZNF407 | ENSP00000240922 | ENSP00000299687 | N-alpha-acetyltransferase 50; N-alpha-acetyltransferase that acetylates the N-terminus of proteins that retain their initiating methionine. Has a broad substrate specificity: able to acetylate the initiator methionine of most peptides, except for those with a proline in second position. Also displays N-epsilon-acetyltransferase activity by mediating acetylation of the side chain of specific lysines on proteins. Autoacetylates in vivo. The relevance of N-epsilon-acetyltransferase activity is however unclear: able to acetylate H4 in vitro, but this result has not been confirmed in vivo. [...] | Zinc finger protein 407; May be involved in transcriptional regulation. | 0.510 |
| SLC66A2 | ADNP2 | ENSP00000380880 | ENSP00000262198 | Solute carrier family 66 member 2. | Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation. | 0.518 |
| SLC66A2 | SMIM21 | ENSP00000380880 | ENSP00000462106 | Solute carrier family 66 member 2. | Small integral membrane protein 21. | 0.470 |
| SLC66A2 | ZNF407 | ENSP00000380880 | ENSP00000299687 | Solute carrier family 66 member 2. | Zinc finger protein 407; May be involved in transcriptional regulation. | 0.577 |
| SLC66A2 | ZNF516 | ENSP00000380880 | ENSP00000394757 | Solute carrier family 66 member 2. | Zinc finger protein 516; Transcriptional regulator that binds to the promoter and activates the transcription of genes promoting brown adipose tissue (BAT) differentiation. Among brown adipose tissue-specific genes, binds the proximal region of the promoter of the UCP1 gene to activate its transcription and thereby regulate thermogenesis (By similarity). May also play a role in the cellular response to replication stress. | 0.553 |
| SMIM21 | ADNP2 | ENSP00000462106 | ENSP00000262198 | Small integral membrane protein 21. | Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation. | 0.424 |
| SMIM21 | SLC66A2 | ENSP00000462106 | ENSP00000380880 | Small integral membrane protein 21. | Solute carrier family 66 member 2. | 0.470 |
| SMIM21 | TSHZ1 | ENSP00000462106 | ENSP00000464391 | Small integral membrane protein 21. | Teashirt homolog 1; Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential). Belongs to the teashirt C2H2-type zinc-finger protein family. | 0.497 |
| SMIM21 | ZADH2 | ENSP00000462106 | ENSP00000323678 | Small integral membrane protein 21. | Prostaglandin reductase 3; Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest efficiency towards 15-keto-PGE2-alpha. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation. | 0.655 |
| SMIM21 | ZNF407 | ENSP00000462106 | ENSP00000299687 | Small integral membrane protein 21. | Zinc finger protein 407; May be involved in transcriptional regulation. | 0.577 |
| SMIM21 | ZNF516 | ENSP00000462106 | ENSP00000394757 | Small integral membrane protein 21. | Zinc finger protein 516; Transcriptional regulator that binds to the promoter and activates the transcription of genes promoting brown adipose tissue (BAT) differentiation. Among brown adipose tissue-specific genes, binds the proximal region of the promoter of the UCP1 gene to activate its transcription and thereby regulate thermogenesis (By similarity). May also play a role in the cellular response to replication stress. | 0.463 |
| SUSD4 | ZNF407 | ENSP00000344219 | ENSP00000299687 | Sushi domain-containing protein 4; Acts as complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b via both the classical and alternative complement pathways. | Zinc finger protein 407; May be involved in transcriptional regulation. | 0.514 |
| TSHZ1 | SMIM21 | ENSP00000464391 | ENSP00000462106 | Teashirt homolog 1; Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential). Belongs to the teashirt C2H2-type zinc-finger protein family. | Small integral membrane protein 21. | 0.497 |
| TSHZ1 | ZADH2 | ENSP00000464391 | ENSP00000323678 | Teashirt homolog 1; Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential). Belongs to the teashirt C2H2-type zinc-finger protein family. | Prostaglandin reductase 3; Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest efficiency towards 15-keto-PGE2-alpha. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation. | 0.728 |
| TSHZ1 | ZNF407 | ENSP00000464391 | ENSP00000299687 | Teashirt homolog 1; Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential). Belongs to the teashirt C2H2-type zinc-finger protein family. | Zinc finger protein 407; May be involved in transcriptional regulation. | 0.610 |
| TSHZ1 | ZNF516 | ENSP00000464391 | ENSP00000394757 | Teashirt homolog 1; Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential). Belongs to the teashirt C2H2-type zinc-finger protein family. | Zinc finger protein 516; Transcriptional regulator that binds to the promoter and activates the transcription of genes promoting brown adipose tissue (BAT) differentiation. Among brown adipose tissue-specific genes, binds the proximal region of the promoter of the UCP1 gene to activate its transcription and thereby regulate thermogenesis (By similarity). May also play a role in the cellular response to replication stress. | 0.598 |