STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSPA4Heat shock 70 kDa protein 4. (806 aa)    
Predicted Functional Partners:
BAG1
BCL2 associated athanogene 1.
    
 0.987
STIP1
Stress induced phosphoprotein 1.
   
 0.987
HSPH1
Heat shock protein family H (Hsp110) member 1.
   
 
 0.985
BAG3
BCL2 associated athanogene 3.
   
 0.973
STUB1
STIP1 homology and U-box containing protein 1.
   
 
 0.968
DNAJB4
DnaJ heat shock protein family (Hsp40) member B4.
  
 0.965
HSP90B1
Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins (By similarity). When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity). Functions in endoplasmic reticulum associated degradation (ERAD) (By similarity). Has ATPase activity. Belongs to the heat shock protein 90 family.
   
 0.965
HSPA5
Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.
  
 
0.963
SNCA
Alpha-synuclein; Belongs to the synuclein family.
    
 0.962
HSPA4L
Heat shock protein family A (Hsp70) member 4 like.
   
   0.956
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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