MYC protein (Canis lupus familiaris) - STRING interaction network

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MYC

Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (452 aa)

Predicted Functional Partners:

CDKN2A

0.901

MAX

0.870

SIRT6

0.842

ZBTB17

0.830

GSK3A

0.816

GSK3B

0.816

ENSCAFP00000062604

0.806

MAPK1

0.788

MAPK3-2

0.748

MAPK3

0.743

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDKN2A	MYC	ENSCAFP00000002445	ENSCAFP00000001523	Cyclin dependent kinase inhibitor 2B.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).	0.901
ENSCAFP00000062604	MAPK1	ENSCAFP00000062604	ENSCAFP00000030998	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.782
ENSCAFP00000062604	MAPK3	ENSCAFP00000062604	ENSCAFP00000025190	Uncharacterized protein.	Mitogen-activated protein kinase.	0.560
ENSCAFP00000062604	MAPK3-2	ENSCAFP00000062604	ENSCAFP00000048201	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.560
ENSCAFP00000062604	MYC	ENSCAFP00000062604	ENSCAFP00000001523	Uncharacterized protein.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).	0.806
ENSCAFP00000062604	ZBTB17	ENSCAFP00000062604	ENSCAFP00000023746	Uncharacterized protein.	Zinc finger and BTB domain containing 17.	0.798
GSK3A	GSK3B	ENSCAFP00000007287	ENSCAFP00000034412	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.881
GSK3A	MYC	ENSCAFP00000007287	ENSCAFP00000001523	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).	0.816
GSK3B	GSK3A	ENSCAFP00000034412	ENSCAFP00000007287	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.881
GSK3B	MYC	ENSCAFP00000034412	ENSCAFP00000001523	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).	0.816
MAPK1	ENSCAFP00000062604	ENSCAFP00000030998	ENSCAFP00000062604	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.782
MAPK1	MAPK3	ENSCAFP00000030998	ENSCAFP00000025190	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.627
MAPK1	MAPK3-2	ENSCAFP00000030998	ENSCAFP00000048201	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.923
MAPK1	MAX	ENSCAFP00000030998	ENSCAFP00000023887	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	MYC associated factor X.	0.782
MAPK1	MYC	ENSCAFP00000030998	ENSCAFP00000001523	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).	0.788
MAPK3	ENSCAFP00000062604	ENSCAFP00000025190	ENSCAFP00000062604	Mitogen-activated protein kinase.	Uncharacterized protein.	0.560
MAPK3	MAPK1	ENSCAFP00000025190	ENSCAFP00000030998	Mitogen-activated protein kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.627
MAPK3	MAX	ENSCAFP00000025190	ENSCAFP00000023887	Mitogen-activated protein kinase.	MYC associated factor X.	0.560
MAPK3	MYC	ENSCAFP00000025190	ENSCAFP00000001523	Mitogen-activated protein kinase.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).	0.743
MAPK3-2	ENSCAFP00000062604	ENSCAFP00000048201	ENSCAFP00000062604	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.560

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