STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ICA1Islet cell autoantigen 1. (514 aa)    
Predicted Functional Partners:
CLNK
Cytokine dependent hematopoietic cell linker.
      
 0.736
MCHR2
Melanin concentrating hormone receptor 2; Belongs to the G-protein coupled receptor 1 family.
      
 0.669
PTPRN
Protein tyrosine phosphatase receptor type N.
   
  
 0.617
NPSR1
Neuropeptide S receptor 1; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
      
 0.585
GLCCI1
Glucocorticoid induced 1.
   
  
 0.581
SEZ6
Seizure related 6 homolog.
      
 0.559
TM7SF2
Transmembrane 7 superfamily member 2.
   
  
 0.542
FCER2
Fc fragment of IgE receptor II.
      
 0.525
SEC24D
SEC24 homolog D, COPII coat complex component.
   
  
 0.522
SORCS1
Sortilin related VPS10 domain containing receptor 1.
      
 0.521
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.