STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ICA1Islet cell autoantigen 1. (514 aa)    
Predicted Functional Partners:
PICK1
Protein interacting with PRKCA 1.
   
 
 0.741
LOC100856647
PKS_ER domain-containing protein.
      
 0.687
CRYZL1
PKS_ER domain-containing protein.
      
 0.687
MCHR2
Melanin concentrating hormone receptor 2; Belongs to the G-protein coupled receptor 1 family.
      
 0.642
CAPN7
Calpain 7; Belongs to the peptidase C2 family.
      
 0.630
CLNK
Cytokine dependent hematopoietic cell linker.
      
 0.623
PTPRN
Protein tyrosine phosphatase receptor type N.
      
 0.595
SLITRK4
SLIT and NTRK like family member 4.
      
 0.594
NPSR1
Neuropeptide S receptor 1; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
      
 0.593
SPTSSB
Serine palmitoyltransferase small subunit B.
      
 0.592
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.