STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NANSN-acetylneuraminate synthase. (491 aa)    
Predicted Functional Partners:
KPNA1
Importin subunit alpha; Functions in nuclear protein import.
   
 
 0.793
ANP32E
Acidic nuclear phosphoprotein 32 family member E.
   
   0.781
ANP32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A; Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase- independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1-mediated transcriptional repression (By similarity).
   
   0.781
VPS72
Vacuolar protein sorting 72 homolog.
    
 
 0.729
ENSCAFP00000059386
Uncharacterized protein.
    
 
 0.729
KPNA6
Importin subunit alpha; Functions in nuclear protein import.
   
 
 0.705
KPNA5
Importin subunit alpha; Functions in nuclear protein import.
   
 
 0.693
F1PWL9_CANLF
Uncharacterized protein.
   
 
 0.664
PTMA
Uncharacterized protein.
   
 
 0.664
ENSCAFP00000053417
Uncharacterized protein.
   
 
 0.664
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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