node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACP3 | KLK2 | ENSCAFP00000058237 | ENSCAFP00000065497 | Acid phosphatase, prostate; Belongs to the histidine acid phosphatase family. | Arginine esterase; This serine protease is found in dog seminal plasma, its exact physiological function is not known. | 0.629 |
AR | KLK1 | ENSCAFP00000024499 | ENSCAFP00000054379 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Peptidase S1 domain-containing protein. | 0.429 |
AR | KLK2 | ENSCAFP00000024499 | ENSCAFP00000065497 | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | Arginine esterase; This serine protease is found in dog seminal plasma, its exact physiological function is not known. | 0.635 |
ELANE | J9NXN6_CANLF | ENSCAFP00000049996 | ENSCAFP00000038049 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | Uncharacterized protein; Belongs to the peptidase S1 family. | 0.552 |
ELANE | KLK1 | ENSCAFP00000049996 | ENSCAFP00000054379 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | Peptidase S1 domain-containing protein. | 0.407 |
ELANE | KLK2 | ENSCAFP00000049996 | ENSCAFP00000065497 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | Arginine esterase; This serine protease is found in dog seminal plasma, its exact physiological function is not known. | 0.558 |
F7 | KLK2 | ENSCAFP00000055494 | ENSCAFP00000065497 | Coagulation factor X. | Arginine esterase; This serine protease is found in dog seminal plasma, its exact physiological function is not known. | 0.569 |
F7 | KNG1 | ENSCAFP00000055494 | ENSCAFP00000020071 | Coagulation factor X. | Kininogen 1. | 0.592 |
J9NXN6_CANLF | ELANE | ENSCAFP00000038049 | ENSCAFP00000049996 | Uncharacterized protein; Belongs to the peptidase S1 family. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.552 |
J9NXN6_CANLF | KLK1 | ENSCAFP00000038049 | ENSCAFP00000054379 | Uncharacterized protein; Belongs to the peptidase S1 family. | Peptidase S1 domain-containing protein. | 0.454 |
J9NXN6_CANLF | KLK2 | ENSCAFP00000038049 | ENSCAFP00000065497 | Uncharacterized protein; Belongs to the peptidase S1 family. | Arginine esterase; This serine protease is found in dog seminal plasma, its exact physiological function is not known. | 0.546 |
J9NXN6_CANLF | PRSS43P | ENSCAFP00000038049 | ENSCAFP00000057639 | Uncharacterized protein; Belongs to the peptidase S1 family. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.524 |
KLK1 | AR | ENSCAFP00000054379 | ENSCAFP00000024499 | Peptidase S1 domain-containing protein. | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | 0.429 |
KLK1 | ELANE | ENSCAFP00000054379 | ENSCAFP00000049996 | Peptidase S1 domain-containing protein. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.407 |
KLK1 | J9NXN6_CANLF | ENSCAFP00000054379 | ENSCAFP00000038049 | Peptidase S1 domain-containing protein. | Uncharacterized protein; Belongs to the peptidase S1 family. | 0.454 |
KLK1 | KLK2 | ENSCAFP00000054379 | ENSCAFP00000065497 | Peptidase S1 domain-containing protein. | Arginine esterase; This serine protease is found in dog seminal plasma, its exact physiological function is not known. | 0.922 |
KLK1 | KNG1 | ENSCAFP00000054379 | ENSCAFP00000020071 | Peptidase S1 domain-containing protein. | Kininogen 1. | 0.869 |
KLK1 | SERPINA4 | ENSCAFP00000054379 | ENSCAFP00000026067 | Peptidase S1 domain-containing protein. | Serpin family A member 4; Belongs to the serpin family. | 0.748 |
KLK2 | ACP3 | ENSCAFP00000065497 | ENSCAFP00000058237 | Arginine esterase; This serine protease is found in dog seminal plasma, its exact physiological function is not known. | Acid phosphatase, prostate; Belongs to the histidine acid phosphatase family. | 0.629 |
KLK2 | AR | ENSCAFP00000065497 | ENSCAFP00000024499 | Arginine esterase; This serine protease is found in dog seminal plasma, its exact physiological function is not known. | Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. | 0.635 |