| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CBY2 | GOLGA2 | ENSCAFP00000040459 | ENSCAFP00000029744 | Component of oligomeric golgi complex 3. | Uncharacterized protein. | 0.529 |
| CBY2 | RAB1A | ENSCAFP00000040459 | ENSCAFP00000040655 | Component of oligomeric golgi complex 3. | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] | 0.835 |
| CBY2 | SCFD1 | ENSCAFP00000040459 | ENSCAFP00000018746 | Component of oligomeric golgi complex 3. | Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. | 0.812 |
| CBY2 | STX5 | ENSCAFP00000040459 | ENSCAFP00000022858 | Component of oligomeric golgi complex 3. | Syntaxin 5; Belongs to the syntaxin family. | 0.877 |
| CBY2 | TRAPPC8 | ENSCAFP00000040459 | ENSCAFP00000040924 | Component of oligomeric golgi complex 3. | Trafficking protein particle complex 8. | 0.670 |
| CBY2 | USO1 | ENSCAFP00000040459 | ENSCAFP00000062029 | Component of oligomeric golgi complex 3. | USO1 vesicle transport factor. | 0.726 |
| CHM | RAB1A | ENSCAFP00000048589 | ENSCAFP00000040655 | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] | 0.866 |
| CHM | RAB7A | ENSCAFP00000048589 | ENSCAFP00000043782 | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | Ras-related protein Rab-7a; Key regulator in endo-lysosomal trafficking. Governs early- to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades (By similarity). Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events, such as growth- factor-mediated cell signaling, nutrient-transportor mediated nutrient uptake, neurotrophin transport in the axons of neurons and lipid metabolism (By simi [...] | 0.959 |
| CHM | TRAPPC8 | ENSCAFP00000048589 | ENSCAFP00000040924 | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | Trafficking protein particle complex 8. | 0.420 |
| GBF1 | RAB1A | ENSCAFP00000014895 | ENSCAFP00000040655 | Golgi brefeldin A resistant guanine nucleotide exchange factor 1. | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] | 0.872 |
| GBF1 | USO1 | ENSCAFP00000014895 | ENSCAFP00000062029 | Golgi brefeldin A resistant guanine nucleotide exchange factor 1. | USO1 vesicle transport factor. | 0.748 |
| GOLGA2 | CBY2 | ENSCAFP00000029744 | ENSCAFP00000040459 | Uncharacterized protein. | Component of oligomeric golgi complex 3. | 0.529 |
| GOLGA2 | RAB1A | ENSCAFP00000029744 | ENSCAFP00000040655 | Uncharacterized protein. | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] | 0.874 |
| GOLGA2 | RAB7A | ENSCAFP00000029744 | ENSCAFP00000043782 | Uncharacterized protein. | Ras-related protein Rab-7a; Key regulator in endo-lysosomal trafficking. Governs early- to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades (By similarity). Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events, such as growth- factor-mediated cell signaling, nutrient-transportor mediated nutrient uptake, neurotrophin transport in the axons of neurons and lipid metabolism (By simi [...] | 0.486 |
| GOLGA2 | SCFD1 | ENSCAFP00000029744 | ENSCAFP00000018746 | Uncharacterized protein. | Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. | 0.719 |
| GOLGA2 | STX5 | ENSCAFP00000029744 | ENSCAFP00000022858 | Uncharacterized protein. | Syntaxin 5; Belongs to the syntaxin family. | 0.974 |
| GOLGA2 | USO1 | ENSCAFP00000029744 | ENSCAFP00000062029 | Uncharacterized protein. | USO1 vesicle transport factor. | 0.912 |
| RAB1A | CBY2 | ENSCAFP00000040655 | ENSCAFP00000040459 | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] | Component of oligomeric golgi complex 3. | 0.835 |
| RAB1A | CHM | ENSCAFP00000040655 | ENSCAFP00000048589 | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | 0.866 |
| RAB1A | GBF1 | ENSCAFP00000040655 | ENSCAFP00000014895 | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] | Golgi brefeldin A resistant guanine nucleotide exchange factor 1. | 0.872 |
