EGFR protein (Canis lupus familiaris) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Score

EGFR

Receptor protein-tyrosine kinase. (1141 aa)

Predicted Functional Partners:

EGF

0.999

GRB2

0.999

HBEGF

0.999

CBL

0.998

PIK3CA

0.998

SOS1

0.997

PIK3R1

0.997

AREG

0.997

STAT3

0.997

TGFA

0.996

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AREG	CBL	ENSCAFP00000039479	ENSCAFP00000046273	Amphiregulin.	Cbl proto-oncogene.	0.520
AREG	EGF	ENSCAFP00000039479	ENSCAFP00000016954	Amphiregulin.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	0.735
AREG	EGFR	ENSCAFP00000039479	ENSCAFP00000005164	Amphiregulin.	Receptor protein-tyrosine kinase.	0.997
AREG	GRB2	ENSCAFP00000039479	ENSCAFP00000049390	Amphiregulin.	Growth factor receptor bound protein 2.	0.505
AREG	HBEGF	ENSCAFP00000039479	ENSCAFP00000051029	Amphiregulin.	Heparin binding EGF like growth factor.	0.616
AREG	PIK3CA	ENSCAFP00000039479	ENSCAFP00000048355	Amphiregulin.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.622
AREG	PIK3R1	ENSCAFP00000039479	ENSCAFP00000011322	Amphiregulin.	Phosphoinositide-3-kinase regulatory subunit 1.	0.537
AREG	SOS1	ENSCAFP00000039479	ENSCAFP00000009512	Amphiregulin.	SOS Ras/Rac guanine nucleotide exchange factor 1.	0.410
AREG	TGFA	ENSCAFP00000039479	ENSCAFP00000005001	Amphiregulin.	EGF-like domain-containing protein.	0.753
CBL	AREG	ENSCAFP00000046273	ENSCAFP00000039479	Cbl proto-oncogene.	Amphiregulin.	0.520
CBL	EGFR	ENSCAFP00000046273	ENSCAFP00000005164	Cbl proto-oncogene.	Receptor protein-tyrosine kinase.	0.998
CBL	GRB2	ENSCAFP00000046273	ENSCAFP00000049390	Cbl proto-oncogene.	Growth factor receptor bound protein 2.	0.996
CBL	HBEGF	ENSCAFP00000046273	ENSCAFP00000051029	Cbl proto-oncogene.	Heparin binding EGF like growth factor.	0.516
CBL	PIK3CA	ENSCAFP00000046273	ENSCAFP00000048355	Cbl proto-oncogene.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.989
CBL	PIK3R1	ENSCAFP00000046273	ENSCAFP00000011322	Cbl proto-oncogene.	Phosphoinositide-3-kinase regulatory subunit 1.	0.995
CBL	SOS1	ENSCAFP00000046273	ENSCAFP00000009512	Cbl proto-oncogene.	SOS Ras/Rac guanine nucleotide exchange factor 1.	0.931
CBL	STAT3	ENSCAFP00000046273	ENSCAFP00000050468	Cbl proto-oncogene.	Signal transducer and activator of transcription.	0.585
EGF	AREG	ENSCAFP00000016954	ENSCAFP00000039479	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	Amphiregulin.	0.735
EGF	EGFR	ENSCAFP00000016954	ENSCAFP00000005164	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	Receptor protein-tyrosine kinase.	0.999
EGF	GRB2	ENSCAFP00000016954	ENSCAFP00000049390	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).	Growth factor receptor bound protein 2.	0.618