STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKMCreatine kinase M-type; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa; Belongs to the ATP:guanido phosphotransferase family. (429 aa)    
Predicted Functional Partners:
CKB
Creatine kinase B-type; Belongs to the ATP:guanido phosphotransferase family.
  
  
 
0.902
MYH6
Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 
 0.885
MYL1
Myosin light chain 1.
   
 
 0.787
MYLPF
Myosin light chain, phosphorylatable, fast skeletal muscle.
   
 
 0.764
CLPB
ClpB homolog, mitochondrial AAA ATPase chaperonin.
  
 
 0.632
CS
Citrate synthase; Belongs to the citrate synthase family.
   
  
 0.624
ASB9
Ankyrin repeat and SOCS box containing 9.
   
 
 0.599
ENSCAFP00000047270
Ldh_1_N domain-containing protein.
   
 
 0.576
ENSCAFP00000062047
Ldh_1_N domain-containing protein.
   
 
 0.576
UTRN
Utrophin.
   
  
 0.575
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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