STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FNTAFarnesyltransferase, CAAX box, alpha. (380 aa)    
Predicted Functional Partners:
FNTB
Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.
   
 0.998
DHDDS
Alkyl transferase; Belongs to the UPP synthase family.
     
 0.966
ZMPSTE24
CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.
     
 0.934
FDFT1
Farnesyl-diphosphate farnesyltransferase 1.
     
 0.934
RCE1
Ras converting CAAX endopeptidase 1.
     
 0.934
PDSS1
Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family.
     
 0.926
PDSS2
Decaprenyl diphosphate synthase subunit 2; Belongs to the FPP/GGPP synthase family.
     
 0.916
NUS1
NUS1 dehydrodolichyl diphosphate synthase subunit.
     
 0.905
ENSCAFP00000045258
Uncharacterized protein.
     
 0.837
FDPS
Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
     
 0.837
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.