STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKT2AKT serine/threonine kinase 2. (557 aa)    
Predicted Functional Partners:
FOXO1
Forkhead box O1.
   
 0.981
FOXO4
Forkhead box O4.
    
 0.972
PDPK1
3-phosphoinositide dependent protein kinase 1.
  
0.970
FOXO3
Forkhead box O3.
    
 0.969
TSC2
TSC complex subunit 2.
    
 0.958
MTOR
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
    
 0.954
AP1G1
PH domain and leucine rich repeat protein phosphatase 2.
   
 0.953
TSC1
TSC complex subunit 1.
    
 0.952
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.952
PHLPP1
PH domain and leucine rich repeat protein phosphatase 1.
    
 0.951
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.