STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PGAM5PGAM family member 5, mitochondrial serine/threonine protein phosphatase. (357 aa)    
Predicted Functional Partners:
FUNDC1
FUN14 domain containing 1.
    
 0.974
KEAP1
Kelch like ECH associated protein 1.
    
 
 0.953
DNM1L
Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
   
 0.939
BCL2L1
BCL2 like 1.
    
 0.921
FUNDC2
FUN14 domain containing 2.
    
 0.873
PINK1
PTEN induced kinase 1.
    
 
 0.857
BPGM
Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
      
 0.852
RBX1
Ring-box 1.
    
 
 0.803
ZRANB1
Zinc finger RANBP2-type containing 1.
    
 
 0.775
PHB2
Prohibitin.
   
 
 0.765
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.