STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AP5S1Adaptor related protein complex 5 subunit sigma 1. (200 aa)    
Predicted Functional Partners:
ARL1
ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family.
      
 0.715
ARFGAP2
ADP ribosylation factor GTPase activating protein 2.
      
 0.707
ZNF367
Zinc finger protein 367.
      
 0.706
ZBTB3
Zinc finger and BTB domain containing 3.
   
  
 0.696
ERMAP
Erythroblast membrane associated protein.
      
 0.694
KAT6B
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
      
 0.641
RHCG
Ammonium transporter Rh type C; Functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion (By similarity); Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
      
 0.637
AP5M1
Adaptor related protein complex 5 subunit mu 1; Belongs to the adaptor complexes medium subunit family.
    
 
 0.591
RND1
Rho family GTPase 1.
      
 0.585
FANCE
FA complementation group E.
      
 0.563
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.