| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BAD | BAK1 | ENSCAFP00000034035 | ENSCAFP00000001448 | BCL2 associated agonist of cell death. | BCL2 antagonist/killer 1. | 0.872 |
| BAD | BAX | ENSCAFP00000034035 | ENSCAFP00000005763 | BCL2 associated agonist of cell death. | BCL2 associated X, apoptosis regulator. | 0.862 |
| BAD | BBC3 | ENSCAFP00000034035 | ENSCAFP00000054385 | BCL2 associated agonist of cell death. | Uncharacterized protein. | 0.409 |
| BAD | BCL2 | ENSCAFP00000034035 | ENSCAFP00000000102 | BCL2 associated agonist of cell death. | Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (By similarity). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity). | 0.997 |
| BAD | BCL2L1 | ENSCAFP00000034035 | ENSCAFP00000010478 | BCL2 associated agonist of cell death. | BCL2 like 1. | 0.997 |
| BAD | BCL2L11 | ENSCAFP00000034035 | ENSCAFP00000046855 | BCL2 associated agonist of cell death. | BCL2 like 11. | 0.927 |
| BAD | CYCS | ENSCAFP00000034035 | ENSCAFP00000004225 | BCL2 associated agonist of cell death. | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.425 |
| BAD | PMAIP1 | ENSCAFP00000034035 | ENSCAFP00000032282 | BCL2 associated agonist of cell death. | Phorbol-12-myristate-13-acetate-induced protein 1; Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 and with BIM/BCL2L11 for binding to MCL1; can displace BAK1 and BIM/BCL2L11 from their binding sites (By similarity). Belongs to the PMAIP1 family. | 0.652 |
| BAD | TP53 | ENSCAFP00000034035 | ENSCAFP00000064590 | BCL2 associated agonist of cell death. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.511 |
| BAK1 | BAD | ENSCAFP00000001448 | ENSCAFP00000034035 | BCL2 antagonist/killer 1. | BCL2 associated agonist of cell death. | 0.872 |
| BAK1 | BAX | ENSCAFP00000001448 | ENSCAFP00000005763 | BCL2 antagonist/killer 1. | BCL2 associated X, apoptosis regulator. | 0.972 |
| BAK1 | BBC3 | ENSCAFP00000001448 | ENSCAFP00000054385 | BCL2 antagonist/killer 1. | Uncharacterized protein. | 0.742 |
| BAK1 | BCL2 | ENSCAFP00000001448 | ENSCAFP00000000102 | BCL2 antagonist/killer 1. | Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (By similarity). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity). | 0.989 |
| BAK1 | BCL2L1 | ENSCAFP00000001448 | ENSCAFP00000010478 | BCL2 antagonist/killer 1. | BCL2 like 1. | 0.995 |
| BAK1 | BCL2L11 | ENSCAFP00000001448 | ENSCAFP00000046855 | BCL2 antagonist/killer 1. | BCL2 like 11. | 0.973 |
| BAK1 | BECN1 | ENSCAFP00000001448 | ENSCAFP00000047143 | BCL2 antagonist/killer 1. | Beclin 1. | 0.609 |
| BAK1 | CYCS | ENSCAFP00000001448 | ENSCAFP00000004225 | BCL2 antagonist/killer 1. | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.983 |
| BAK1 | PMAIP1 | ENSCAFP00000001448 | ENSCAFP00000032282 | BCL2 antagonist/killer 1. | Phorbol-12-myristate-13-acetate-induced protein 1; Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 and with BIM/BCL2L11 for binding to MCL1; can displace BAK1 and BIM/BCL2L11 from their binding sites (By similarity). Belongs to the PMAIP1 family. | 0.819 |
| BAK1 | TP53 | ENSCAFP00000001448 | ENSCAFP00000064590 | BCL2 antagonist/killer 1. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.995 |
| BAX | BAD | ENSCAFP00000005763 | ENSCAFP00000034035 | BCL2 associated X, apoptosis regulator. | BCL2 associated agonist of cell death. | 0.862 |
