STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (770 aa)    
Predicted Functional Partners:
PLXNB1
Plexin B1.
   
 0.940
PLXNB3
Plexin B3.
   
 0.939
RNF135
Ring finger protein 135.
   
  
 0.708
PCGF1
Polycomb group ring finger 1.
   
 
 0.702
KCNIP4
Potassium voltage-gated channel interacting protein 4.
   
  
 0.682
WDR11
WD repeat domain 11.
      
 0.653
DQX1
DEAQ-box RNA dependent ATPase 1.
   
 
 0.648
RND3
Rho family GTPase 3.
    
 0.555
PLEKHA5
Pleckstrin homology domain containing A5.
   
  
 0.519
EPHB6
EPH receptor B6.
   
 
 0.507
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.