node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMELX | GH1 | ENSCAFP00000017046 | ENSCAFP00000018659 | Amelogenin X isoform. | Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues; Belongs to the somatotropin/prolactin family. | 0.920 |
AMELX | LOC478196 | ENSCAFP00000017046 | ENSCAFP00000046922 | Amelogenin X isoform. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.922 |
AMELX | OPTC | ENSCAFP00000017046 | ENSCAFP00000013921 | Amelogenin X isoform. | Opticin; Inhibits angiogenesis in the vitreous humor of the eye, and therefore represses neovascularization (By similarity). Binds collagen fibrils (By similarity). May be involved in collagen fiber organization via regulation of other members of the small leucine-rich repeat proteoglycan superfamily (By similarity). | 0.846 |
AMELX | PRPH2 | ENSCAFP00000017046 | ENSCAFP00000002506 | Amelogenin X isoform. | Peripherin-2; Essential for retina photoreceptor outer segment disk morphogenesis, may also play a role with ROM1 in the maintenance of outer segment disk structure (By similarity). Required for the maintenance of retinal outer nuclear layer thickness (By similarity). Required for the correct development and organization of the photoreceptor inner segment (By similarity). Belongs to the PRPH2/ROM1 family. | 0.922 |
GH1 | AMELX | ENSCAFP00000018659 | ENSCAFP00000017046 | Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues; Belongs to the somatotropin/prolactin family. | Amelogenin X isoform. | 0.920 |
GH1 | LOC478196 | ENSCAFP00000018659 | ENSCAFP00000046922 | Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues; Belongs to the somatotropin/prolactin family. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.919 |
GH1 | OPTC | ENSCAFP00000018659 | ENSCAFP00000013921 | Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues; Belongs to the somatotropin/prolactin family. | Opticin; Inhibits angiogenesis in the vitreous humor of the eye, and therefore represses neovascularization (By similarity). Binds collagen fibrils (By similarity). May be involved in collagen fiber organization via regulation of other members of the small leucine-rich repeat proteoglycan superfamily (By similarity). | 0.846 |
GH1 | PRPH2 | ENSCAFP00000018659 | ENSCAFP00000002506 | Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues; Belongs to the somatotropin/prolactin family. | Peripherin-2; Essential for retina photoreceptor outer segment disk morphogenesis, may also play a role with ROM1 in the maintenance of outer segment disk structure (By similarity). Required for the maintenance of retinal outer nuclear layer thickness (By similarity). Required for the correct development and organization of the photoreceptor inner segment (By similarity). Belongs to the PRPH2/ROM1 family. | 0.920 |
GUCY2F | HELZ | ENSCAFP00000026657 | ENSCAFP00000016801 | Guanylate cyclase. | Helicase with zinc finger. | 0.587 |
GUCY2F | OPTC | ENSCAFP00000026657 | ENSCAFP00000013921 | Guanylate cyclase. | Opticin; Inhibits angiogenesis in the vitreous humor of the eye, and therefore represses neovascularization (By similarity). Binds collagen fibrils (By similarity). May be involved in collagen fiber organization via regulation of other members of the small leucine-rich repeat proteoglycan superfamily (By similarity). | 0.785 |
GUCY2F | PRPH2 | ENSCAFP00000026657 | ENSCAFP00000002506 | Guanylate cyclase. | Peripherin-2; Essential for retina photoreceptor outer segment disk morphogenesis, may also play a role with ROM1 in the maintenance of outer segment disk structure (By similarity). Required for the maintenance of retinal outer nuclear layer thickness (By similarity). Required for the correct development and organization of the photoreceptor inner segment (By similarity). Belongs to the PRPH2/ROM1 family. | 0.605 |
HELZ | GUCY2F | ENSCAFP00000016801 | ENSCAFP00000026657 | Helicase with zinc finger. | Guanylate cyclase. | 0.587 |
HELZ | OPTC | ENSCAFP00000016801 | ENSCAFP00000013921 | Helicase with zinc finger. | Opticin; Inhibits angiogenesis in the vitreous humor of the eye, and therefore represses neovascularization (By similarity). Binds collagen fibrils (By similarity). May be involved in collagen fiber organization via regulation of other members of the small leucine-rich repeat proteoglycan superfamily (By similarity). | 0.762 |
LOC478196 | AMELX | ENSCAFP00000046922 | ENSCAFP00000017046 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | Amelogenin X isoform. | 0.922 |
LOC478196 | GH1 | ENSCAFP00000046922 | ENSCAFP00000018659 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues; Belongs to the somatotropin/prolactin family. | 0.919 |
LOC478196 | OPTC | ENSCAFP00000046922 | ENSCAFP00000013921 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | Opticin; Inhibits angiogenesis in the vitreous humor of the eye, and therefore represses neovascularization (By similarity). Binds collagen fibrils (By similarity). May be involved in collagen fiber organization via regulation of other members of the small leucine-rich repeat proteoglycan superfamily (By similarity). | 0.824 |
LOC478196 | PRPH2 | ENSCAFP00000046922 | ENSCAFP00000002506 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | Peripherin-2; Essential for retina photoreceptor outer segment disk morphogenesis, may also play a role with ROM1 in the maintenance of outer segment disk structure (By similarity). Required for the maintenance of retinal outer nuclear layer thickness (By similarity). Required for the correct development and organization of the photoreceptor inner segment (By similarity). Belongs to the PRPH2/ROM1 family. | 0.922 |
MMP13 | MMP2 | ENSCAFP00000022174 | ENSCAFP00000013872 | Matrix metallopeptidase 13. | Matrix metallopeptidase 2. | 0.683 |
MMP13 | MMP7 | ENSCAFP00000022174 | ENSCAFP00000030464 | Matrix metallopeptidase 13. | Matrix metallopeptidase 7. | 0.625 |
MMP13 | OPTC | ENSCAFP00000022174 | ENSCAFP00000013921 | Matrix metallopeptidase 13. | Opticin; Inhibits angiogenesis in the vitreous humor of the eye, and therefore represses neovascularization (By similarity). Binds collagen fibrils (By similarity). May be involved in collagen fiber organization via regulation of other members of the small leucine-rich repeat proteoglycan superfamily (By similarity). | 0.753 |