STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
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[Homology]
Score
PEBP1Hippocampal cholinergic neurostimulating peptide; Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). Involved in the positive regulation of epithelial cell migration. Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation (By similarity). Belongs to the [...] (243 aa)    
Predicted Functional Partners:
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
   
 0.841
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
   
 0.840
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.777
DAP3
Death associated protein 3.
   
 
 0.693
MRPL44
Mitochondrial ribosomal protein L44.
   
 
 0.678
MRPL46
Mitochondrial ribosomal protein L46.
   
 
 0.671
MRPL10
Mitochondrial ribosomal protein L10.
   
 
 0.667
MRPL40
Mitochondrial ribosomal protein L40.
   
 
 0.666
MRPL19
Mitochondrial ribosomal protein L19.
   
 
 0.654
MRPL4
Mitochondrial ribosomal protein L4.
   
 
 0.652
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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