| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKR1C3 | HPGDS | ENSCAFP00000007901 | ENSCAFP00000061205 | Aldo_ket_red domain-containing protein. | Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily. | 0.929 |
| AKR1C3 | PTGDS | ENSCAFP00000007901 | ENSCAFP00000046976 | Aldo_ket_red domain-containing protein. | Prostaglandin-H2 D-isomerase; Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophobic molecules and as a secretory retinoid and thyroid hormone transporter. Possib [...] | 0.815 |
| AKR1C3 | PTGES | ENSCAFP00000007901 | ENSCAFP00000040771 | Aldo_ket_red domain-containing protein. | Prostaglandin E synthase; Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). | 0.695 |
| AKR1C3 | TBXAS1 | ENSCAFP00000007901 | ENSCAFP00000005960 | Aldo_ket_red domain-containing protein. | Thromboxane A synthase 1; Belongs to the cytochrome P450 family. | 0.402 |
| GSR | GSTO1 | ENSCAFP00000009702 | ENSCAFP00000015576 | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Glutathione S-transferase omega 1; Belongs to the GST superfamily. | 0.941 |
| GSR | GSTO2 | ENSCAFP00000009702 | ENSCAFP00000058513 | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Glutathione S-transferase omega 2; Belongs to the GST superfamily. | 0.932 |
| GSR | HPGDS | ENSCAFP00000009702 | ENSCAFP00000061205 | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily. | 0.927 |
| GSR | PRDX6 | ENSCAFP00000009702 | ENSCAFP00000052928 | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Peroxiredoxin 6. | 0.881 |
| GSR | PTGES | ENSCAFP00000009702 | ENSCAFP00000040771 | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Prostaglandin E synthase; Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). | 0.589 |
| GSTO1 | GSR | ENSCAFP00000015576 | ENSCAFP00000009702 | Glutathione S-transferase omega 1; Belongs to the GST superfamily. | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.941 |
| GSTO1 | GSTO2 | ENSCAFP00000015576 | ENSCAFP00000058513 | Glutathione S-transferase omega 1; Belongs to the GST superfamily. | Glutathione S-transferase omega 2; Belongs to the GST superfamily. | 0.965 |
| GSTO1 | HPGDS | ENSCAFP00000015576 | ENSCAFP00000061205 | Glutathione S-transferase omega 1; Belongs to the GST superfamily. | Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily. | 0.962 |
| GSTO1 | PRDX6 | ENSCAFP00000015576 | ENSCAFP00000052928 | Glutathione S-transferase omega 1; Belongs to the GST superfamily. | Peroxiredoxin 6. | 0.923 |
| GSTO1 | PTGES | ENSCAFP00000015576 | ENSCAFP00000040771 | Glutathione S-transferase omega 1; Belongs to the GST superfamily. | Prostaglandin E synthase; Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). | 0.698 |
| GSTO2 | GSR | ENSCAFP00000058513 | ENSCAFP00000009702 | Glutathione S-transferase omega 2; Belongs to the GST superfamily. | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.932 |
| GSTO2 | GSTO1 | ENSCAFP00000058513 | ENSCAFP00000015576 | Glutathione S-transferase omega 2; Belongs to the GST superfamily. | Glutathione S-transferase omega 1; Belongs to the GST superfamily. | 0.965 |
| GSTO2 | HPGDS | ENSCAFP00000058513 | ENSCAFP00000061205 | Glutathione S-transferase omega 2; Belongs to the GST superfamily. | Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily. | 0.947 |
| GSTO2 | PRDX6 | ENSCAFP00000058513 | ENSCAFP00000052928 | Glutathione S-transferase omega 2; Belongs to the GST superfamily. | Peroxiredoxin 6. | 0.949 |
| GSTO2 | PTGES | ENSCAFP00000058513 | ENSCAFP00000040771 | Glutathione S-transferase omega 2; Belongs to the GST superfamily. | Prostaglandin E synthase; Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). | 0.698 |
| HPGDS | AKR1C3 | ENSCAFP00000061205 | ENSCAFP00000007901 | Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily. | Aldo_ket_red domain-containing protein. | 0.929 |
