HPCA protein (Canis lupus familiaris) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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co-expression

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[Homology]

Score

HPCA

Hippocalcin. (303 aa)

Predicted Functional Partners:

CACNB4

0.617

LOC477516

0.568

NT5E

0.534

CACNA2D2

0.528

CALB2

0.523

ITPR1

0.514

KCNF1

0.508

SLC32A1

0.507

PI4KB

0.478

MYL12B

0.421

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CACNA2D2	CACNB4	ENSCAFP00000015492	ENSCAFP00000055439	Calcium voltage-gated channel auxiliary subunit alpha2delta 2.	Calcium voltage-gated channel auxiliary subunit beta 4.	0.942
CACNA2D2	HPCA	ENSCAFP00000015492	ENSCAFP00000015339	Calcium voltage-gated channel auxiliary subunit alpha2delta 2.	Hippocalcin.	0.528
CACNB4	CACNA2D2	ENSCAFP00000055439	ENSCAFP00000015492	Calcium voltage-gated channel auxiliary subunit beta 4.	Calcium voltage-gated channel auxiliary subunit alpha2delta 2.	0.942
CACNB4	HPCA	ENSCAFP00000055439	ENSCAFP00000015339	Calcium voltage-gated channel auxiliary subunit beta 4.	Hippocalcin.	0.617
CACNB4	ITPR1	ENSCAFP00000055439	ENSCAFP00000008870	Calcium voltage-gated channel auxiliary subunit beta 4.	Inositol 1,4,5-trisphosphate receptor type 1.	0.414
CALB2	HPCA	ENSCAFP00000029919	ENSCAFP00000015339	Calbindin 2.	Hippocalcin.	0.523
CALB2	SLC32A1	ENSCAFP00000029919	ENSCAFP00000013195	Calbindin 2.	Solute carrier family 32 member 1.	0.445
HPCA	CACNA2D2	ENSCAFP00000015339	ENSCAFP00000015492	Hippocalcin.	Calcium voltage-gated channel auxiliary subunit alpha2delta 2.	0.528
HPCA	CACNB4	ENSCAFP00000015339	ENSCAFP00000055439	Hippocalcin.	Calcium voltage-gated channel auxiliary subunit beta 4.	0.617
HPCA	CALB2	ENSCAFP00000015339	ENSCAFP00000029919	Hippocalcin.	Calbindin 2.	0.523
HPCA	ITPR1	ENSCAFP00000015339	ENSCAFP00000008870	Hippocalcin.	Inositol 1,4,5-trisphosphate receptor type 1.	0.514
HPCA	KCNF1	ENSCAFP00000015339	ENSCAFP00000005187	Hippocalcin.	Potassium voltage-gated channel modifier subfamily F member 1; Belongs to the potassium channel family.	0.508
HPCA	LOC477516	ENSCAFP00000015339	ENSCAFP00000041203	Hippocalcin.	Uncharacterized protein.	0.568
HPCA	MYL12B	ENSCAFP00000015339	ENSCAFP00000059211	Hippocalcin.	Uncharacterized protein.	0.421
HPCA	NT5E	ENSCAFP00000015339	ENSCAFP00000004456	Hippocalcin.	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	0.534
HPCA	PI4KB	ENSCAFP00000015339	ENSCAFP00000018623	Hippocalcin.	Phosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family.	0.478
HPCA	SLC32A1	ENSCAFP00000015339	ENSCAFP00000013195	Hippocalcin.	Solute carrier family 32 member 1.	0.507
ITPR1	CACNB4	ENSCAFP00000008870	ENSCAFP00000055439	Inositol 1,4,5-trisphosphate receptor type 1.	Calcium voltage-gated channel auxiliary subunit beta 4.	0.414
ITPR1	HPCA	ENSCAFP00000008870	ENSCAFP00000015339	Inositol 1,4,5-trisphosphate receptor type 1.	Hippocalcin.	0.514
ITPR1	LOC477516	ENSCAFP00000008870	ENSCAFP00000041203	Inositol 1,4,5-trisphosphate receptor type 1.	Uncharacterized protein.	0.662