STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TGM1Protein-glutamine gamma-glutamyltransferase K; Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum. Involved in cell proliferation (By similarity); Belongs to the transglutaminase superfamily. Transglutaminase family. (816 aa)    
Predicted Functional Partners:
PNPLA1
PNPLA domain-containing protein.
   
  
 0.875
NIPAL4
NIPA like domain containing 4.
   
  
 0.858
PPL
Periplakin.
   
 
 0.835
CDSN
Corneodesmosin.
   
 
 0.833
ABCA12
ATP binding cassette subfamily A member 12.
   
  
 0.829
CYP4F22
Cytochrome P450 family 4 subfamily F member 22; Belongs to the cytochrome P450 family.
   
  
 0.817
SLC27A4
Solute carrier family 27 member 4.
   
  
 0.803
CERS3
Ceramide synthase 3.
   
 
 0.789
EVPL
Envoplakin.
   
 
 0.772
ASPRV1
Aspartic peptidase retroviral like 1.
   
  
 0.737
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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