STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHA5Pleckstrin homology domain containing A5. (1284 aa)    
Predicted Functional Partners:
ZMAT3
Zinc finger matrin-type 3.
    
 
 0.901
PDZD11
PDZ domain containing 11.
    
 0.901
TCEA1
Transcription elongation factor A1.
    
 
 0.892
EIF5
Non-specific serine/threonine protein kinase.
    
 
 0.883
MYCT1
MYC target 1.
      
 0.865
CERS6
Ceramide synthase 6.
    
 
 0.827
RGS20
Regulator of G protein signaling 20.
    
 
 0.700
ADGRA1
Adhesion G protein-coupled receptor A1.
    
 
 0.582
FRMD4B
FERM domain containing 4B.
    
 0.555
FRMD4A
FERM domain containing 4A.
    
 0.555
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.