STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ICA1LIslet cell autoantigen 1 like. (493 aa)    
Predicted Functional Partners:
PICK1
Protein interacting with PRKCA 1.
   
 
 0.741
FAM117B
Family with sequence similarity 117 member B.
      
 0.692
NBEAL1
Neurobeachin like 1.
      
 0.560
CYP20A1
Cytochrome P450 family 20 subfamily A member 1.
      
 0.526
ADAD1
Adenosine deaminase domain containing 1.
      
 0.525
MTCH2
Mitochondrial carrier 2; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.524
RAB2A
Ras-related protein Rab-2A; Required for protein transport from the endoplasmic reticulum to the Golgi complex.
    
 
 0.500
RAB2B
RAB2B, member RAS oncogene family.
    
 
 0.500
ENSCAFP00000050945
Uncharacterized protein.
    
 
 0.500
OPA3
Outer mitochondrial membrane lipid metabolism regulator OPA3.
      
 0.486
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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