CD52 protein (Canis lupus familiaris) - STRING interaction network

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Score

CD52

CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role. (67 aa)

Predicted Functional Partners:

WFDC2

0.889

NPC2-2

0.889

CD3E

0.851

CORO1A

0.751

CD2

0.750

CD53

0.729

CD48

0.630

SEPTIN1

0.618

S100A16

0.581

CD19

0.573

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD19	CD2	ENSCAFP00000025493	ENSCAFP00000014445	CD19 molecule.	CD2 molecule.	0.636
CD19	CD3E	ENSCAFP00000025493	ENSCAFP00000052947	CD19 molecule.	T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...]	0.880
CD19	CD48	ENSCAFP00000025493	ENSCAFP00000061136	CD19 molecule.	CD48 molecule.	0.490
CD19	CD52	ENSCAFP00000025493	ENSCAFP00000018435	CD19 molecule.	CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role.	0.573
CD2	CD19	ENSCAFP00000014445	ENSCAFP00000025493	CD2 molecule.	CD19 molecule.	0.636
CD2	CD3E	ENSCAFP00000014445	ENSCAFP00000052947	CD2 molecule.	T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...]	0.938
CD2	CD48	ENSCAFP00000014445	ENSCAFP00000061136	CD2 molecule.	CD48 molecule.	0.704
CD2	CD52	ENSCAFP00000014445	ENSCAFP00000018435	CD2 molecule.	CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role.	0.750
CD2	CD53	ENSCAFP00000014445	ENSCAFP00000048986	CD2 molecule.	Tetraspanin.	0.541
CD3E	CD19	ENSCAFP00000052947	ENSCAFP00000025493	T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...]	CD19 molecule.	0.880
CD3E	CD2	ENSCAFP00000052947	ENSCAFP00000014445	T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...]	CD2 molecule.	0.938
CD3E	CD48	ENSCAFP00000052947	ENSCAFP00000061136	T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...]	CD48 molecule.	0.452
CD3E	CD52	ENSCAFP00000052947	ENSCAFP00000018435	T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...]	CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role.	0.851
CD3E	SEPTIN1	ENSCAFP00000052947	ENSCAFP00000024393	T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...]	Septin 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	0.573
CD48	CD19	ENSCAFP00000061136	ENSCAFP00000025493	CD48 molecule.	CD19 molecule.	0.490
CD48	CD2	ENSCAFP00000061136	ENSCAFP00000014445	CD48 molecule.	CD2 molecule.	0.704
CD48	CD3E	ENSCAFP00000061136	ENSCAFP00000052947	CD48 molecule.	T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...]	0.452
CD48	CD52	ENSCAFP00000061136	ENSCAFP00000018435	CD48 molecule.	CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role.	0.630
CD48	CD53	ENSCAFP00000061136	ENSCAFP00000048986	CD48 molecule.	Tetraspanin.	0.799
CD48	CORO1A	ENSCAFP00000061136	ENSCAFP00000053109	CD48 molecule.	Coronin; Belongs to the WD repeat coronin family.	0.447

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