| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EIF3A | RAB1B | ENSCAFP00000017766 | ENSCAFP00000048766 | Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] | RAB1B, member RAS oncogene family. | 0.735 |
| EIF3A | SUPT16H | ENSCAFP00000017766 | ENSCAFP00000008366 | Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] | SPT16 homolog, facilitates chromatin remodeling subunit. | 0.927 |
| PPP1CC | RAB1B | ENSCAFP00000030520 | ENSCAFP00000048766 | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Dephosphorylates RPS6KB1. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density- asso [...] | RAB1B, member RAS oncogene family. | 0.692 |
| RAB1A | RAB1B | ENSCAFP00000040655 | ENSCAFP00000048766 | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] | RAB1B, member RAS oncogene family. | 0.902 |
| RAB1A | TBC1D20 | ENSCAFP00000040655 | ENSCAFP00000040784 | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] | TBC1 domain family member 20. | 0.881 |
| RAB1A | TRAPPC1 | ENSCAFP00000040655 | ENSCAFP00000024852 | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] | Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. | 0.866 |
| RAB1A | TRAPPC2 | ENSCAFP00000040655 | ENSCAFP00000017291 | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] | Trafficking protein particle complex subunit 2; Prevents ENO1-mediated transcriptional repression and antagonizes ENO1-mediated cell death. May play a role in vesicular transport from endoplasmic reticulum to Golgi (By similarity). | 0.835 |
| RAB1A | TRAPPC3 | ENSCAFP00000040655 | ENSCAFP00000005241 | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] | Trafficking protein particle complex subunit; May play a role in vesicular transport from endoplasmic reticulum to Golgi. | 0.829 |
| RAB1A | TRAPPC3L | ENSCAFP00000040655 | ENSCAFP00000041634 | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] | Trafficking protein particle complex subunit; May play a role in vesicular transport from endoplasmic reticulum to Golgi. | 0.667 |
| RAB1A | TRAPPC8 | ENSCAFP00000040655 | ENSCAFP00000040924 | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] | Trafficking protein particle complex 8. | 0.848 |
| RAB1B | EIF3A | ENSCAFP00000048766 | ENSCAFP00000017766 | RAB1B, member RAS oncogene family. | Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] | 0.735 |
| RAB1B | PPP1CC | ENSCAFP00000048766 | ENSCAFP00000030520 | RAB1B, member RAS oncogene family. | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Dephosphorylates RPS6KB1. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density- asso [...] | 0.692 |
| RAB1B | RAB1A | ENSCAFP00000048766 | ENSCAFP00000040655 | RAB1B, member RAS oncogene family. | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] | 0.902 |
| RAB1B | SUPT16H | ENSCAFP00000048766 | ENSCAFP00000008366 | RAB1B, member RAS oncogene family. | SPT16 homolog, facilitates chromatin remodeling subunit. | 0.739 |
| RAB1B | TBC1D20 | ENSCAFP00000048766 | ENSCAFP00000040784 | RAB1B, member RAS oncogene family. | TBC1 domain family member 20. | 0.861 |
| RAB1B | TRAPPC1 | ENSCAFP00000048766 | ENSCAFP00000024852 | RAB1B, member RAS oncogene family. | Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. | 0.760 |
| RAB1B | TRAPPC2 | ENSCAFP00000048766 | ENSCAFP00000017291 | RAB1B, member RAS oncogene family. | Trafficking protein particle complex subunit 2; Prevents ENO1-mediated transcriptional repression and antagonizes ENO1-mediated cell death. May play a role in vesicular transport from endoplasmic reticulum to Golgi (By similarity). | 0.678 |
| RAB1B | TRAPPC3 | ENSCAFP00000048766 | ENSCAFP00000005241 | RAB1B, member RAS oncogene family. | Trafficking protein particle complex subunit; May play a role in vesicular transport from endoplasmic reticulum to Golgi. | 0.669 |
| RAB1B | TRAPPC3L | ENSCAFP00000048766 | ENSCAFP00000041634 | RAB1B, member RAS oncogene family. | Trafficking protein particle complex subunit; May play a role in vesicular transport from endoplasmic reticulum to Golgi. | 0.667 |
| RAB1B | TRAPPC8 | ENSCAFP00000048766 | ENSCAFP00000040924 | RAB1B, member RAS oncogene family. | Trafficking protein particle complex 8. | 0.755 |