SLC2A3 protein (Canis lupus familiaris) - STRING interaction network

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SLC2A3

Solute carrier family 2, facilitated glucose transporter member 3; Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. (509 aa)

Predicted Functional Partners:

TP53

0.741

NANOGNB

0.692

INS

0.645

SLC1A5

0.634

RAB14

0.624

HK2

0.624

SLC22A2

0.615

CNTRL

0.584

HIF1A

0.584

HK1

0.572

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNTRL	SLC2A3	ENSCAFP00000050376	ENSCAFP00000052705	Centriolin.	Solute carrier family 2, facilitated glucose transporter member 3; Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.	0.584
HIF1A	HK1	ENSCAFP00000064837	ENSCAFP00000020540	Uncharacterized protein.	Hexokinase 1.	0.589
HIF1A	HK2	ENSCAFP00000064837	ENSCAFP00000012208	Uncharacterized protein.	Hexokinase 2.	0.633
HIF1A	INS	ENSCAFP00000064837	ENSCAFP00000051648	Uncharacterized protein.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.510
HIF1A	SLC2A3	ENSCAFP00000064837	ENSCAFP00000052705	Uncharacterized protein.	Solute carrier family 2, facilitated glucose transporter member 3; Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.	0.584
HIF1A	TP53	ENSCAFP00000064837	ENSCAFP00000064590	Uncharacterized protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]	0.978
HK1	HIF1A	ENSCAFP00000020540	ENSCAFP00000064837	Hexokinase 1.	Uncharacterized protein.	0.589
HK1	HK2	ENSCAFP00000020540	ENSCAFP00000012208	Hexokinase 1.	Hexokinase 2.	0.993
HK1	INS	ENSCAFP00000020540	ENSCAFP00000051648	Hexokinase 1.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.688
HK1	SLC2A3	ENSCAFP00000020540	ENSCAFP00000052705	Hexokinase 1.	Solute carrier family 2, facilitated glucose transporter member 3; Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.	0.572
HK2	HIF1A	ENSCAFP00000012208	ENSCAFP00000064837	Hexokinase 2.	Uncharacterized protein.	0.633
HK2	HK1	ENSCAFP00000012208	ENSCAFP00000020540	Hexokinase 2.	Hexokinase 1.	0.993
HK2	INS	ENSCAFP00000012208	ENSCAFP00000051648	Hexokinase 2.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.648
HK2	SLC2A3	ENSCAFP00000012208	ENSCAFP00000052705	Hexokinase 2.	Solute carrier family 2, facilitated glucose transporter member 3; Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.	0.624
HK2	TP53	ENSCAFP00000012208	ENSCAFP00000064590	Hexokinase 2.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]	0.475
INS	HIF1A	ENSCAFP00000051648	ENSCAFP00000064837	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein.	0.510
INS	HK1	ENSCAFP00000051648	ENSCAFP00000020540	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Hexokinase 1.	0.688
INS	HK2	ENSCAFP00000051648	ENSCAFP00000012208	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Hexokinase 2.	0.648
INS	SLC1A5	ENSCAFP00000051648	ENSCAFP00000050639	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Amino acid transporter.	0.466
INS	SLC2A3	ENSCAFP00000051648	ENSCAFP00000052705	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Solute carrier family 2, facilitated glucose transporter member 3; Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.	0.645

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