FN1 protein (Canis lupus familiaris) - STRING interaction network

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FN1

Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). (2586 aa)

Predicted Functional Partners:

ITGA5

0.995

ITGB1

0.994

ITGAV

0.986

ITGB3

0.984

SDC4

0.962

ITGB5

0.955

ITGB6

0.953

ITGB2

0.949

ITGB7

0.941

ITGA8

0.940

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FN1	ITGA5	ENSCAFP00000066679	ENSCAFP00000009742	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Integrin subunit alpha 5; Belongs to the integrin alpha chain family.	0.995
FN1	ITGA8	ENSCAFP00000066679	ENSCAFP00000006951	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Integrin subunit alpha 8; Belongs to the integrin alpha chain family.	0.940
FN1	ITGAV	ENSCAFP00000066679	ENSCAFP00000050990	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Integrin subunit alpha V; Belongs to the integrin alpha chain family.	0.986
FN1	ITGB1	ENSCAFP00000066679	ENSCAFP00000005722	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Integrin beta; Belongs to the integrin beta chain family.	0.994
FN1	ITGB2	ENSCAFP00000066679	ENSCAFP00000059524	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Integrin beta.	0.949
FN1	ITGB3	ENSCAFP00000066679	ENSCAFP00000032511	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Integrin beta; Belongs to the integrin beta chain family.	0.984
FN1	ITGB5	ENSCAFP00000066679	ENSCAFP00000040050	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Integrin beta; Belongs to the integrin beta chain family.	0.955
FN1	ITGB6	ENSCAFP00000066679	ENSCAFP00000014567	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Integrin beta; Belongs to the integrin beta chain family.	0.953
FN1	ITGB7	ENSCAFP00000066679	ENSCAFP00000054149	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Integrin beta; Belongs to the integrin beta chain family.	0.941
FN1	SDC4	ENSCAFP00000066679	ENSCAFP00000058875	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Syndecan 4.	0.962
ITGA5	FN1	ENSCAFP00000009742	ENSCAFP00000066679	Integrin subunit alpha 5; Belongs to the integrin alpha chain family.	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	0.995
ITGA5	ITGA8	ENSCAFP00000009742	ENSCAFP00000006951	Integrin subunit alpha 5; Belongs to the integrin alpha chain family.	Integrin subunit alpha 8; Belongs to the integrin alpha chain family.	0.551
ITGA5	ITGAV	ENSCAFP00000009742	ENSCAFP00000050990	Integrin subunit alpha 5; Belongs to the integrin alpha chain family.	Integrin subunit alpha V; Belongs to the integrin alpha chain family.	0.469
ITGA5	ITGB1	ENSCAFP00000009742	ENSCAFP00000005722	Integrin subunit alpha 5; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.999
ITGA5	ITGB2	ENSCAFP00000009742	ENSCAFP00000059524	Integrin subunit alpha 5; Belongs to the integrin alpha chain family.	Integrin beta.	0.962
ITGA5	ITGB3	ENSCAFP00000009742	ENSCAFP00000032511	Integrin subunit alpha 5; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.997
ITGA5	ITGB5	ENSCAFP00000009742	ENSCAFP00000040050	Integrin subunit alpha 5; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.942
ITGA5	ITGB6	ENSCAFP00000009742	ENSCAFP00000014567	Integrin subunit alpha 5; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.936
ITGA5	ITGB7	ENSCAFP00000009742	ENSCAFP00000054149	Integrin subunit alpha 5; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.961
ITGA8	FN1	ENSCAFP00000006951	ENSCAFP00000066679	Integrin subunit alpha 8; Belongs to the integrin alpha chain family.	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	0.940

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