STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDC42Cell division cycle 42. (191 aa)    
Predicted Functional Partners:
PAK4
Non-specific serine/threonine protein kinase.
   
 0.985
PAK1
Non-specific serine/threonine protein kinase.
   
 0.973
ARHGDIA
Rho GDP dissociation inhibitor alpha.
   
 0.972
PAK3
P21 (RAC1) activated kinase 3.
   
 0.944
PAK2
Non-specific serine/threonine protein kinase.
   
 0.937
LOC100856635
Uncharacterized protein.
    
 0.902
ARHGEF7
Rho guanine nucleotide exchange factor 7.
   
 0.891
ITSN2
Intersectin 2.
    
 
 0.887
IQGAP1
IQ motif containing GTPase activating protein 1.
   
 0.887
SRC
Tyrosine-protein kinase.
   
 0.870
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.