STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
INCENPInner centromere protein. (905 aa)    
Predicted Functional Partners:
CDCA8
Cell division cycle associated 8.
   
 0.999
AURKB
Aurora kinase B; Belongs to the protein kinase superfamily.
   
 0.999
PLK1
Serine/threonine-protein kinase PLK.
   
 0.964
CDC20
Cell division cycle 20.
   
 
 0.940
NUDC
Nuclear distribution C, dynein complex regulator.
   
 
 0.922
KIF23
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.904
HASPIN
Histone H3 associated protein kinase.
   
  
 0.900
KIF11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.898
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.898
AURKC
Aurora kinase C; Belongs to the protein kinase superfamily.
   
 
 0.890
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.