STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOB1Transducer of ERBB2, 1. (492 aa)    
Predicted Functional Partners:
CNOT7
CCR4-NOT transcription complex subunit 7.
   
 0.873
CNOT2
CCR4-NOT transcription complex subunit 2.
    
 0.845
CNOT10
CCR4-NOT transcription complex subunit 10.
    
 0.821
CNOT11
CCR4-NOT transcription complex subunit 11.
    
 0.818
CNOT3
CCR4-NOT transcription complex subunit 3.
    
 0.816
CNOT1
CCR4-NOT transcription complex subunit 1.
    
 0.807
CNOT8
CCR4-NOT transcription complex subunit 8.
    
 0.795
TNKS1BP1
Tankyrase 1 binding protein 1.
    
  0.785
CNOT6
CCR4-NOT transcription complex subunit 6.
    
 0.775
CNOT6L
CCR4-NOT transcription complex subunit 6 like.
    
 
 0.718
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.