node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTR2 | CORO2B | ENSCAFP00000051199 | ENSCAFP00000059372 | Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. | Coronin; Belongs to the WD repeat coronin family. | 0.510 |
ARHGEF2 | CORO2B | ENSCAFP00000057462 | ENSCAFP00000059372 | Rho guanine nucleotide exchange factor 2; Activates Rho-GTPases by promoting the exchange of GDP for GTP. May be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Binds Rac-GTPases, but does not seem to promote nucleotide exchange activity toward Rac-GTPases. May stimulate instead the cortical activity of Rac. Inactive toward CDC42, TC10, or Ras- GTPases. Forms an intracellular sensing system along with NOD1 for the detec [...] | Coronin; Belongs to the WD repeat coronin family. | 0.683 |
ARHGEF2 | PALLD | ENSCAFP00000057462 | ENSCAFP00000050535 | Rho guanine nucleotide exchange factor 2; Activates Rho-GTPases by promoting the exchange of GDP for GTP. May be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Binds Rac-GTPases, but does not seem to promote nucleotide exchange activity toward Rac-GTPases. May stimulate instead the cortical activity of Rac. Inactive toward CDC42, TC10, or Ras- GTPases. Forms an intracellular sensing system along with NOD1 for the detec [...] | Palladin, cytoskeletal associated protein. | 0.406 |
CNPY2 | CORO2B | ENSCAFP00000000169 | ENSCAFP00000059372 | Saposin B-type domain-containing protein. | Coronin; Belongs to the WD repeat coronin family. | 0.637 |
CORO2B | ACTR2 | ENSCAFP00000059372 | ENSCAFP00000051199 | Coronin; Belongs to the WD repeat coronin family. | Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. | 0.510 |
CORO2B | ARHGEF2 | ENSCAFP00000059372 | ENSCAFP00000057462 | Coronin; Belongs to the WD repeat coronin family. | Rho guanine nucleotide exchange factor 2; Activates Rho-GTPases by promoting the exchange of GDP for GTP. May be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Binds Rac-GTPases, but does not seem to promote nucleotide exchange activity toward Rac-GTPases. May stimulate instead the cortical activity of Rac. Inactive toward CDC42, TC10, or Ras- GTPases. Forms an intracellular sensing system along with NOD1 for the detec [...] | 0.683 |
CORO2B | CNPY2 | ENSCAFP00000059372 | ENSCAFP00000000169 | Coronin; Belongs to the WD repeat coronin family. | Saposin B-type domain-containing protein. | 0.637 |
CORO2B | FEM1B | ENSCAFP00000059372 | ENSCAFP00000025753 | Coronin; Belongs to the WD repeat coronin family. | Fem-1 homolog B. | 0.542 |
CORO2B | FPGS | ENSCAFP00000059372 | ENSCAFP00000029808 | Coronin; Belongs to the WD repeat coronin family. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.560 |
CORO2B | MRPL39 | ENSCAFP00000059372 | ENSCAFP00000056116 | Coronin; Belongs to the WD repeat coronin family. | Mitochondrial ribosomal protein L39. | 0.630 |
CORO2B | PALLD | ENSCAFP00000059372 | ENSCAFP00000050535 | Coronin; Belongs to the WD repeat coronin family. | Palladin, cytoskeletal associated protein. | 0.596 |
CORO2B | RNF34 | ENSCAFP00000059372 | ENSCAFP00000012198 | Coronin; Belongs to the WD repeat coronin family. | Ring finger protein 34. | 0.509 |
CORO2B | WDR13 | ENSCAFP00000059372 | ENSCAFP00000022809 | Coronin; Belongs to the WD repeat coronin family. | WD repeat domain 13. | 0.588 |
CORO2B | ZNF768 | ENSCAFP00000059372 | ENSCAFP00000039056 | Coronin; Belongs to the WD repeat coronin family. | Zinc finger protein 768. | 0.515 |
FEM1B | CORO2B | ENSCAFP00000025753 | ENSCAFP00000059372 | Fem-1 homolog B. | Coronin; Belongs to the WD repeat coronin family. | 0.542 |
FPGS | CORO2B | ENSCAFP00000029808 | ENSCAFP00000059372 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Coronin; Belongs to the WD repeat coronin family. | 0.560 |
MRPL39 | CORO2B | ENSCAFP00000056116 | ENSCAFP00000059372 | Mitochondrial ribosomal protein L39. | Coronin; Belongs to the WD repeat coronin family. | 0.630 |
PALLD | ARHGEF2 | ENSCAFP00000050535 | ENSCAFP00000057462 | Palladin, cytoskeletal associated protein. | Rho guanine nucleotide exchange factor 2; Activates Rho-GTPases by promoting the exchange of GDP for GTP. May be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Binds Rac-GTPases, but does not seem to promote nucleotide exchange activity toward Rac-GTPases. May stimulate instead the cortical activity of Rac. Inactive toward CDC42, TC10, or Ras- GTPases. Forms an intracellular sensing system along with NOD1 for the detec [...] | 0.406 |
PALLD | CORO2B | ENSCAFP00000050535 | ENSCAFP00000059372 | Palladin, cytoskeletal associated protein. | Coronin; Belongs to the WD repeat coronin family. | 0.596 |
RNF34 | CORO2B | ENSCAFP00000012198 | ENSCAFP00000059372 | Ring finger protein 34. | Coronin; Belongs to the WD repeat coronin family. | 0.509 |