| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMBP | UMOD | ENSCAFP00000004896 | ENSCAFP00000040807 | Alpha-1-microglobulin/bikunin precursor. | Uromodulin, secreted form; [Uromodulin]: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability. May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelia. | 0.615 |
| AQP2 | SLC12A3 | ENSCAFP00000039918 | ENSCAFP00000013283 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Solute carrier family 12 member 3. | 0.523 |
| AQP2 | UMOD | ENSCAFP00000039918 | ENSCAFP00000040807 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Uromodulin, secreted form; [Uromodulin]: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability. May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelia. | 0.643 |
| CEL | LOC478196 | ENSCAFP00000054562 | ENSCAFP00000046922 | Carboxyl ester lipase; Belongs to the type-B carboxylesterase/lipase family. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.973 |
| CEL | PPY | ENSCAFP00000054562 | ENSCAFP00000021236 | Carboxyl ester lipase; Belongs to the type-B carboxylesterase/lipase family. | Pancreatic icosapeptide; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions. | 0.837 |
| CEL | RTN1 | ENSCAFP00000054562 | ENSCAFP00000035337 | Carboxyl ester lipase; Belongs to the type-B carboxylesterase/lipase family. | Reticulon. | 0.561 |
| CEL | SLC13A1 | ENSCAFP00000054562 | ENSCAFP00000005317 | Carboxyl ester lipase; Belongs to the type-B carboxylesterase/lipase family. | Solute carrier family 13 member 1. | 0.538 |
| CEL | UMOD | ENSCAFP00000054562 | ENSCAFP00000040807 | Carboxyl ester lipase; Belongs to the type-B carboxylesterase/lipase family. | Uromodulin, secreted form; [Uromodulin]: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability. May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelia. | 0.638 |
| LOC478196 | CEL | ENSCAFP00000046922 | ENSCAFP00000054562 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | Carboxyl ester lipase; Belongs to the type-B carboxylesterase/lipase family. | 0.973 |
| LOC478196 | PPY | ENSCAFP00000046922 | ENSCAFP00000021236 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | Pancreatic icosapeptide; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions. | 0.858 |
| LOC478196 | SLC13A1 | ENSCAFP00000046922 | ENSCAFP00000005317 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | Solute carrier family 13 member 1. | 0.532 |
| LOC478196 | UMOD | ENSCAFP00000046922 | ENSCAFP00000040807 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | Uromodulin, secreted form; [Uromodulin]: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability. May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelia. | 0.784 |
| PPY | CEL | ENSCAFP00000021236 | ENSCAFP00000054562 | Pancreatic icosapeptide; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions. | Carboxyl ester lipase; Belongs to the type-B carboxylesterase/lipase family. | 0.837 |
| PPY | LOC478196 | ENSCAFP00000021236 | ENSCAFP00000046922 | Pancreatic icosapeptide; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.858 |
| PPY | SLC13A1 | ENSCAFP00000021236 | ENSCAFP00000005317 | Pancreatic icosapeptide; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions. | Solute carrier family 13 member 1. | 0.465 |
| PPY | UMOD | ENSCAFP00000021236 | ENSCAFP00000040807 | Pancreatic icosapeptide; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions. | Uromodulin, secreted form; [Uromodulin]: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability. May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelia. | 0.844 |
| RTN1 | CEL | ENSCAFP00000035337 | ENSCAFP00000054562 | Reticulon. | Carboxyl ester lipase; Belongs to the type-B carboxylesterase/lipase family. | 0.561 |
| RTN1 | SLC13A1 | ENSCAFP00000035337 | ENSCAFP00000005317 | Reticulon. | Solute carrier family 13 member 1. | 0.531 |
| RTN1 | UMOD | ENSCAFP00000035337 | ENSCAFP00000040807 | Reticulon. | Uromodulin, secreted form; [Uromodulin]: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability. May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelia. | 0.609 |
| SEC61A1 | UMOD | ENSCAFP00000037921 | ENSCAFP00000040807 | Protein transport protein Sec61 subunit alpha isoform 1. | Uromodulin, secreted form; [Uromodulin]: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability. May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelia. | 0.630 |
