STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XYLT1Xylosyltransferase 1; Catalyzes the first step in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans, such as DCN. Transfers D- xylose from UDP-D-xylose to specific serine residues of the core protein. Required for normal maturation of chondrocytes during bone development, normal onset of ossification and normal embryonic and postnatal skeleton development, especially of the long bones. (915 aa)    
Predicted Functional Partners:
B4GALT7
Beta-1,4-galactosyltransferase 7.
     
 0.849
EXTL2
Exostosin like glycosyltransferase 2.
      
 0.799
EXTL3
Exostosin like glycosyltransferase 3; Belongs to the glycosyltransferase 47 family.
      
 0.730
FAM20B
FAM20B glycosaminoglycan xylosylkinase.
      
 0.684
KMT2B
Lysine methyltransferase 2B.
      
 0.607
NELFA
Negative elongation factor complex member A.
    
 0.600
SCFD2
Sec1 family domain containing 2; Belongs to the STXBP/unc-18/SEC1 family.
      
 0.598
PROSER3
Uncharacterized protein.
    
 
 0.595
AMER3
APC membrane recruitment protein 3.
      
 0.591
SDC1
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
    
 
 0.557
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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