STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLFN14Schlafen family member 14. (957 aa)    
Predicted Functional Partners:
VCL
Vinculin.
    
 
 0.728
EVA1B
Eva-1 homolog B.
      
 0.714
REL
REL proto-oncogene, NF-kB subunit.
      
 0.679
AFAP1L1
Actin filament associated protein 1 like 1.
      
 0.548
MGP
Matrix Gla protein; Associates with the organic matrix of bone and cartilage.
      
 0.530
RSAD2
Radical S-adenosyl methionine domain containing 2.
   
  
 0.439
VPS53
VPS53 subunit of GARP complex.
      
 0.418
RPH3AL
Rabphilin 3A like (without C2 domains).
      
 0.418
SERGEF
Secretion regulating guanine nucleotide exchange factor.
    
 
 0.410
SYT10
Synaptotagmin 10.
      
 0.408
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.