node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADM | CKB | ENSCAFP00000011183 | ENSCAFP00000058712 | Proadrenomedullin N-20 terminal peptide; AM and PAMP are potent hypotensive and vasodilatator agents; Belongs to the adrenomedullin family. | Creatine kinase B-type; Belongs to the ATP:guanido phosphotransferase family. | 0.567 |
ASB9 | CKB | ENSCAFP00000017519 | ENSCAFP00000058712 | Ankyrin repeat and SOCS box containing 9. | Creatine kinase B-type; Belongs to the ATP:guanido phosphotransferase family. | 0.695 |
ASB9 | CKM | ENSCAFP00000017519 | ENSCAFP00000041666 | Ankyrin repeat and SOCS box containing 9. | Creatine kinase M-type; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa; Belongs to the ATP:guanido phosphotransferase family. | 0.599 |
ASB9 | MTPN | ENSCAFP00000017519 | ENSCAFP00000039244 | Ankyrin repeat and SOCS box containing 9. | Myotrophin; Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer (By similarity). | 0.498 |
CKB | ADM | ENSCAFP00000058712 | ENSCAFP00000011183 | Creatine kinase B-type; Belongs to the ATP:guanido phosphotransferase family. | Proadrenomedullin N-20 terminal peptide; AM and PAMP are potent hypotensive and vasodilatator agents; Belongs to the adrenomedullin family. | 0.567 |
CKB | ASB9 | ENSCAFP00000058712 | ENSCAFP00000017519 | Creatine kinase B-type; Belongs to the ATP:guanido phosphotransferase family. | Ankyrin repeat and SOCS box containing 9. | 0.695 |
CKB | CKM | ENSCAFP00000058712 | ENSCAFP00000041666 | Creatine kinase B-type; Belongs to the ATP:guanido phosphotransferase family. | Creatine kinase M-type; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa; Belongs to the ATP:guanido phosphotransferase family. | 0.902 |
CKB | CLPB | ENSCAFP00000058712 | ENSCAFP00000065447 | Creatine kinase B-type; Belongs to the ATP:guanido phosphotransferase family. | ClpB homolog, mitochondrial AAA ATPase chaperonin. | 0.632 |
CKB | ENSCAFP00000047270 | ENSCAFP00000058712 | ENSCAFP00000047270 | Creatine kinase B-type; Belongs to the ATP:guanido phosphotransferase family. | Ldh_1_N domain-containing protein. | 0.596 |
CKB | ENSCAFP00000062047 | ENSCAFP00000058712 | ENSCAFP00000062047 | Creatine kinase B-type; Belongs to the ATP:guanido phosphotransferase family. | Ldh_1_N domain-containing protein. | 0.596 |
CKB | HPDL | ENSCAFP00000058712 | ENSCAFP00000006895 | Creatine kinase B-type; Belongs to the ATP:guanido phosphotransferase family. | 4-hydroxyphenylpyruvate dioxygenase. | 0.571 |
CKB | MTPN | ENSCAFP00000058712 | ENSCAFP00000039244 | Creatine kinase B-type; Belongs to the ATP:guanido phosphotransferase family. | Myotrophin; Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer (By similarity). | 0.656 |
CKB | MYL1 | ENSCAFP00000058712 | ENSCAFP00000000161 | Creatine kinase B-type; Belongs to the ATP:guanido phosphotransferase family. | Myosin light chain 1. | 0.569 |
CKB | PPP1CC | ENSCAFP00000058712 | ENSCAFP00000030520 | Creatine kinase B-type; Belongs to the ATP:guanido phosphotransferase family. | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Dephosphorylates RPS6KB1. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density- asso [...] | 0.566 |
CKM | ASB9 | ENSCAFP00000041666 | ENSCAFP00000017519 | Creatine kinase M-type; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa; Belongs to the ATP:guanido phosphotransferase family. | Ankyrin repeat and SOCS box containing 9. | 0.599 |
CKM | CKB | ENSCAFP00000041666 | ENSCAFP00000058712 | Creatine kinase M-type; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa; Belongs to the ATP:guanido phosphotransferase family. | Creatine kinase B-type; Belongs to the ATP:guanido phosphotransferase family. | 0.902 |
CKM | CLPB | ENSCAFP00000041666 | ENSCAFP00000065447 | Creatine kinase M-type; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa; Belongs to the ATP:guanido phosphotransferase family. | ClpB homolog, mitochondrial AAA ATPase chaperonin. | 0.632 |
CKM | ENSCAFP00000047270 | ENSCAFP00000041666 | ENSCAFP00000047270 | Creatine kinase M-type; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa; Belongs to the ATP:guanido phosphotransferase family. | Ldh_1_N domain-containing protein. | 0.576 |
CKM | ENSCAFP00000062047 | ENSCAFP00000041666 | ENSCAFP00000062047 | Creatine kinase M-type; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa; Belongs to the ATP:guanido phosphotransferase family. | Ldh_1_N domain-containing protein. | 0.576 |
CKM | MYL1 | ENSCAFP00000041666 | ENSCAFP00000000161 | Creatine kinase M-type; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa; Belongs to the ATP:guanido phosphotransferase family. | Myosin light chain 1. | 0.787 |