MARCHF2 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANGPTL4	MARCHF2	ENSCAFP00000027322	ENSCAFP00000056574	Angiopoietin like 4.	Membrane associated ring-CH-type finger 2.	0.606
CFTR	MARCHF2	ENSCAFP00000005112	ENSCAFP00000056574	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Membrane associated ring-CH-type finger 2.	0.495
CNOT2	MARCHF2	ENSCAFP00000056484	ENSCAFP00000056574	CCR4-NOT transcription complex subunit 2.	Membrane associated ring-CH-type finger 2.	0.480
DAD1	MARCHF2	ENSCAFP00000016393	ENSCAFP00000056574	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	Membrane associated ring-CH-type finger 2.	0.594
DAD1	RNF24	ENSCAFP00000016393	ENSCAFP00000009222	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	Ring finger protein 24.	0.419
DGCR2	MARCHF2	ENSCAFP00000021850	ENSCAFP00000056574	DiGeorge syndrome critical region gene 2.	Membrane associated ring-CH-type finger 2.	0.623
DGCR2	OXA1L	ENSCAFP00000021850	ENSCAFP00000016422	DiGeorge syndrome critical region gene 2.	OXA1L mitochondrial inner membrane protein.	0.422
DGCR2	RNF24	ENSCAFP00000021850	ENSCAFP00000009222	DiGeorge syndrome critical region gene 2.	Ring finger protein 24.	0.416
IGHM	MARCHF2	ENSCAFP00000027249	ENSCAFP00000056574	Ig mu chain C region.	Membrane associated ring-CH-type finger 2.	0.489
IGHM	OXA1L	ENSCAFP00000027249	ENSCAFP00000016422	Ig mu chain C region.	OXA1L mitochondrial inner membrane protein.	0.534
MARCHF2	ANGPTL4	ENSCAFP00000056574	ENSCAFP00000027322	Membrane associated ring-CH-type finger 2.	Angiopoietin like 4.	0.606
MARCHF2	CFTR	ENSCAFP00000056574	ENSCAFP00000005112	Membrane associated ring-CH-type finger 2.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	0.495
MARCHF2	CNOT2	ENSCAFP00000056574	ENSCAFP00000056484	Membrane associated ring-CH-type finger 2.	CCR4-NOT transcription complex subunit 2.	0.480
MARCHF2	DAD1	ENSCAFP00000056574	ENSCAFP00000016393	Membrane associated ring-CH-type finger 2.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	0.594
MARCHF2	DGCR2	ENSCAFP00000056574	ENSCAFP00000021850	Membrane associated ring-CH-type finger 2.	DiGeorge syndrome critical region gene 2.	0.623
MARCHF2	IGHM	ENSCAFP00000056574	ENSCAFP00000027249	Membrane associated ring-CH-type finger 2.	Ig mu chain C region.	0.489
MARCHF2	OXA1L	ENSCAFP00000056574	ENSCAFP00000016422	Membrane associated ring-CH-type finger 2.	OXA1L mitochondrial inner membrane protein.	0.688
MARCHF2	RNF24	ENSCAFP00000056574	ENSCAFP00000009222	Membrane associated ring-CH-type finger 2.	Ring finger protein 24.	0.687
MARCHF2	STX10	ENSCAFP00000056574	ENSCAFP00000025111	Membrane associated ring-CH-type finger 2.	Syntaxin 10; Belongs to the syntaxin family.	0.529
MARCHF2	STX6	ENSCAFP00000056574	ENSCAFP00000018902	Membrane associated ring-CH-type finger 2.	Syntaxin 6; Belongs to the syntaxin family.	0.529