STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GP2Pancreatic secretory granule membrane major glycoprotein GP2. (519 aa)    
Predicted Functional Partners:
NPC1
NPC intracellular cholesterol transporter 1.
   
  
 0.821
LOC478196
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 
 0.772
MAF1
Repressor of RNA polymerase III transcription MAF1; Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA. Belongs to the MAF1 family.
      
 0.769
PPY
Pancreatic icosapeptide; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions.
   
 
 0.740
GP6
Glycoprotein VI platelet.
   
 
 0.730
CUZD1
CUB and zona pellucida like domains 1.
   
 
0.708
TNFAIP2
TNF alpha induced protein 2.
    
 
 0.671
GPR85
G protein-coupled receptor 85.
    
 
 0.649
SIGLEC1
Sialic acid binding Ig like lectin 1.
   
 
 0.640
HPD
4-hydroxyphenylpyruvate dioxygenase; Belongs to the 4HPPD family.
   
  
 0.618
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.