DDX39B protein (Canis lupus familiaris) - STRING interaction network

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DDX39B

Spliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pat [...] (428 aa)

Predicted Functional Partners:

ALYREF

0.984

SARNP

0.920

SRRT

0.917

THOC3

0.910

RBM8A

0.909

THOC1

0.906

EIF4A3

0.904

THOC7

0.903

THOC6

0.895

DHX8

0.893

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALYREF	DDX39B	ENSCAFP00000008786	ENSCAFP00000031897	Aly/REF export factor.	Spliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pat [...]	0.984
ALYREF	DHX8	ENSCAFP00000008786	ENSCAFP00000021473	Aly/REF export factor.	DEAH-box helicase 8.	0.882
ALYREF	EIF4A3	ENSCAFP00000008786	ENSCAFP00000008399	Aly/REF export factor.	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	0.989
ALYREF	RBM8A	ENSCAFP00000008786	ENSCAFP00000016512	Aly/REF export factor.	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.	0.948
ALYREF	SARNP	ENSCAFP00000008786	ENSCAFP00000049004	Aly/REF export factor.	SAP domain containing ribonucleoprotein.	0.881
ALYREF	SRRT	ENSCAFP00000008786	ENSCAFP00000020650	Aly/REF export factor.	Serrate, RNA effector molecule.	0.976
ALYREF	THOC1	ENSCAFP00000008786	ENSCAFP00000027073	Aly/REF export factor.	THO complex 1.	0.997
ALYREF	THOC3	ENSCAFP00000008786	ENSCAFP00000021131	Aly/REF export factor.	THO complex 3.	0.998
ALYREF	THOC6	ENSCAFP00000008786	ENSCAFP00000052846	Aly/REF export factor.	THO complex 6.	0.937
ALYREF	THOC7	ENSCAFP00000008786	ENSCAFP00000030992	Aly/REF export factor.	THO complex 7.	0.980
DDX39B	ALYREF	ENSCAFP00000031897	ENSCAFP00000008786	Spliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pat [...]	Aly/REF export factor.	0.984
DDX39B	DHX8	ENSCAFP00000031897	ENSCAFP00000021473	Spliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pat [...]	DEAH-box helicase 8.	0.893
DDX39B	EIF4A3	ENSCAFP00000031897	ENSCAFP00000008399	Spliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pat [...]	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	0.904
DDX39B	RBM8A	ENSCAFP00000031897	ENSCAFP00000016512	Spliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pat [...]	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.	0.909
DDX39B	SARNP	ENSCAFP00000031897	ENSCAFP00000049004	Spliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pat [...]	SAP domain containing ribonucleoprotein.	0.920
DDX39B	SRRT	ENSCAFP00000031897	ENSCAFP00000020650	Spliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pat [...]	Serrate, RNA effector molecule.	0.917
DDX39B	THOC1	ENSCAFP00000031897	ENSCAFP00000027073	Spliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pat [...]	THO complex 1.	0.906
DDX39B	THOC3	ENSCAFP00000031897	ENSCAFP00000021131	Spliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pat [...]	THO complex 3.	0.910
DDX39B	THOC6	ENSCAFP00000031897	ENSCAFP00000052846	Spliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pat [...]	THO complex 6.	0.895
DDX39B	THOC7	ENSCAFP00000031897	ENSCAFP00000030992	Spliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pat [...]	THO complex 7.	0.903

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