STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEK2NIMA related kinase 2. (444 aa)    
Predicted Functional Partners:
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B.
   
 0.996
ANAPC4
Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family.
   
 0.979
FZR1
Fizzy and cell division cycle 20 related 1.
   
 
 0.978
CDC20
Cell division cycle 20.
   
 0.977
CDC27
Cell division cycle 27.
   
 0.976
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 
 0.967
CDC23
Cell division cycle 23.
   
 0.961
ANAPC1
Anaphase promoting complex subunit 1.
   
 0.955
CDC20B
Cell division cycle 20B.
   
 
 0.949
CDC16
Cell division cycle 16.
   
 0.940
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.