STRINGSTRING
FGF5 protein (Canis lupus) - STRING interaction network
"FGF5" - Fibroblast growth factor 5 in Canis lupus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FGF5Fibroblast growth factor 5; Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase (270 aa)    
Predicted Functional Partners:
FGFR1
Fibroblast growth factor receptor 1 (822 aa)
       
  0.977
FGFR2
Canis lupus familiaris fibroblast growth factor receptor 2 (FGFR2), mRNA (841 aa)
       
  0.970
FGFR3
Fibroblast growth factor receptor 3 (801 aa)
       
  0.950
MAPK1
Canis lupus familiaris mitogen-activated protein kinase 1 (MAPK1), mRNA (360 aa)
       
  0.936
ENSCAFG00000018974
Uncharacterized protein (336 aa)
       
  0.936
MAPK3
Mitogen-activated protein kinase 3 (361 aa)
       
  0.936
HRAS
HRas proto-oncogene, GTPase (248 aa)
       
  0.936
KL
Klotho (806 aa)
       
  0.933
FGFRL1
Fibroblast growth factor receptor-like 1 (423 aa)
       
  0.931
FRS2
Fibroblast growth factor receptor substrate 2 (508 aa)
         
  0.929
Your Current Organism:
Canis lupus
NCBI taxonomy Id: 9612
Other names: C. lupus, Canis familiaris, Canis lupus, gray wolf, grey wolf
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