Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LINGO2Leucine rich repeat and Ig domain containing 2. (606 aa)    
Predicted Functional Partners:
NSG2
Neuronal vesicle trafficking associated 2.
   
  
 0.862
GRXCR2
Glutaredoxin and cysteine rich domain containing 2.
      
 0.852
CASTOR2
Uncharacterized protein.
      
 0.827
TECRL
Trans-2,3-enoyl-CoA reductase like.
     
 0.817
LINGO1
Leucine rich repeat and Ig domain containing 1.
   
   0.786
UBASH3B
Ubiquitin associated and SH3 domain containing B.
      
 0.777
LGALSL
Galectin.
   
  
 0.727
ACTR3B
Actin related protein 3B; Belongs to the actin family.
    
 
 0.701
AMOTL1
Angiomotin like 1.
    
 
 0.698
MRS2
Magnesium transporter.
      
 0.694
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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