HDAC1 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHD3	CHD4	ENSCAFP00000024834	ENSCAFP00000022067	Chromodomain helicase DNA binding protein 3.	Chromodomain helicase DNA binding protein 4.	0.999
CHD3	CHD5	ENSCAFP00000024834	ENSCAFP00000053537	Chromodomain helicase DNA binding protein 3.	Chromodomain helicase DNA binding protein 5.	0.997
CHD3	HDAC1	ENSCAFP00000024834	ENSCAFP00000036819	Chromodomain helicase DNA binding protein 3.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.988
CHD3	HDAC2	ENSCAFP00000024834	ENSCAFP00000042408	Chromodomain helicase DNA binding protein 3.	Histone deacetylase 2.	0.986
CHD3	MTA2	ENSCAFP00000024834	ENSCAFP00000023249	Chromodomain helicase DNA binding protein 3.	Metastasis associated 1 family member 2.	0.994
CHD3	MTA3	ENSCAFP00000024834	ENSCAFP00000009773	Chromodomain helicase DNA binding protein 3.	Metastasis associated 1 family member 3.	0.987
CHD3	PTPN9	ENSCAFP00000024834	ENSCAFP00000042090	Chromodomain helicase DNA binding protein 3.	SIN3 transcription regulator family member A.	0.478
CHD3	RCOR1	ENSCAFP00000024834	ENSCAFP00000026701	Chromodomain helicase DNA binding protein 3.	REST corepressor 1.	0.703
CHD3	SAP30	ENSCAFP00000024834	ENSCAFP00000011613	Chromodomain helicase DNA binding protein 3.	Sin3A associated protein 30.	0.656
CHD3	SAP30L	ENSCAFP00000024834	ENSCAFP00000026019	Chromodomain helicase DNA binding protein 3.	SAP30 like.	0.590
CHD4	CHD3	ENSCAFP00000022067	ENSCAFP00000024834	Chromodomain helicase DNA binding protein 4.	Chromodomain helicase DNA binding protein 3.	0.999
CHD4	CHD5	ENSCAFP00000022067	ENSCAFP00000053537	Chromodomain helicase DNA binding protein 4.	Chromodomain helicase DNA binding protein 5.	0.998
CHD4	HDAC1	ENSCAFP00000022067	ENSCAFP00000036819	Chromodomain helicase DNA binding protein 4.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.996
CHD4	HDAC2	ENSCAFP00000022067	ENSCAFP00000042408	Chromodomain helicase DNA binding protein 4.	Histone deacetylase 2.	0.996
CHD4	MTA2	ENSCAFP00000022067	ENSCAFP00000023249	Chromodomain helicase DNA binding protein 4.	Metastasis associated 1 family member 2.	0.997
CHD4	MTA3	ENSCAFP00000022067	ENSCAFP00000009773	Chromodomain helicase DNA binding protein 4.	Metastasis associated 1 family member 3.	0.994
CHD4	PTPN9	ENSCAFP00000022067	ENSCAFP00000042090	Chromodomain helicase DNA binding protein 4.	SIN3 transcription regulator family member A.	0.517
CHD4	RCOR1	ENSCAFP00000022067	ENSCAFP00000026701	Chromodomain helicase DNA binding protein 4.	REST corepressor 1.	0.719
CHD4	SAP30	ENSCAFP00000022067	ENSCAFP00000011613	Chromodomain helicase DNA binding protein 4.	Sin3A associated protein 30.	0.711
CHD4	SAP30L	ENSCAFP00000022067	ENSCAFP00000026019	Chromodomain helicase DNA binding protein 4.	SAP30 like.	0.589