Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
COL17A1120 kDa linear IgA disease antigen homolog; The 120 kDa linear IgA disease antigen homolog is an anchoring filament component involved in dermal-epidermal cohesion. (1597 aa)    
Predicted Functional Partners:
ITGB4
Integrin beta.
   
 0.906
LAMB3
Laminin subunit beta 3.
   
 0.839
LAMC2
Laminin subunit gamma 2.
   
 0.804
LAMA3
Laminin subunit alpha 3.
   
 0.754
XPR1
Uncharacterized protein.
      
 0.692
ENAM
Enamelin.
    
 
 0.684
FAM83H
Family with sequence similarity 83 member H.
      
 0.669
AMTN
Amelotin.
      
 0.667
PLEC
Plectin.
   
 
 0.651
DST
Dystonin.
   
 
 0.648
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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