STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NUDT4Nudix hydrolase 4. (181 aa)    
Predicted Functional Partners:
NUDT12
Nudix hydrolase 12.
  
 0.880
NUDT18
Nudix hydrolase 18; Belongs to the Nudix hydrolase family.
     
 0.872
NUDT5
Nudix hydrolase 5; Belongs to the Nudix hydrolase family.
      
 0.865
NUDT6
Nudix hydrolase 6; Belongs to the Nudix hydrolase family.
     
 0.862
NUDT17
Nudix hydrolase 17.
      
 0.853
NUDT22
Nudix hydrolase 22.
      
 0.852
NUDT21
Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]
   
  
 0.829
NUDT14
Nudix hydrolase 14.
      
 0.816
NUDT9
Nudix hydrolase 9.
    
 0.813
NUDT7
Nudix hydrolase 7.
      
 0.713
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.