STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (405 aa)    
Predicted Functional Partners:
TPX2
TPX2 microtubule nucleation factor.
   
 0.976
PLK1
Serine/threonine-protein kinase PLK.
   
0.926
CPEB1
RRM domain-containing protein.
   
 0.920
PTTG1
Uncharacterized protein.
   
 0.918
CPEB3
Cytoplasmic polyadenylation element binding protein 3.
   
 0.908
CPEB2
Cytoplasmic polyadenylation element binding protein 2.
   
 0.908
CPEB4
Cytoplasmic polyadenylation element binding protein 4.
   
 0.908
PHLDA1
Pleckstrin homology like domain family A member 1.
   
 
 0.902
GADD45A
Growth arrest and DNA damage inducible alpha.
     
  0.900
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
  
0.891
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.