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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM170BTransmembrane protein 170B. (202 aa)    
Predicted Functional Partners:
TMEM168
Transmembrane protein 168.
   
  
 0.492
SH2B3
SH2B adaptor protein 3.
      
 0.489
TCEA3
Transcription elongation factor A3.
   
  
 0.485
J9P902_CANLF
TFIIS N-terminal domain-containing protein.
      
 0.485
FZD8
Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family.
      
 0.480
FZD5
Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family.
      
 0.480
TMEM236
Transmembrane protein 236.
   
  
 0.453
TMEM64
Transmembrane protein 64.
   
  
 0.405
LRRC32
Leucine rich repeat containing 32.
   
  
 0.403
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.